Olanzapine induced tardive dyskinesia treated successfully with quetiapine: a case report.

摘要

"Tardive dyskinesia" (TD) denotes abnormal, involuntary movements of the tongue, jaw, trunk and extremities which develop after at least 3 months of exposure to a dopamine blocking agent. The symptoms either arise while under treatment, or may develop within 4 weeks of withdrawal from an oral agent In either case; the symptoms should be present for at least 4 weeks (APA, 1994). The prevalence of TD in patients receiving antipsychotic treatment varies between 0.5% and 62.0% (Egan et al., 1997). The relationship of olanzapine and TD is controversial and there have been case reports of TD due to olanzapine treatment, as well as its use in treating TD. Here, we report a case of TD which arose after prolonged use of olanzapine and may have responded to a treatment regimen with quetiapine.