A case of venlafaxine-induced bruxism alleviated by duloxetine substitution.

摘要

Bruxism, characterized by clenching and/or grinding of dentition, is a common condition affecting 8-21% of the population (Attansio, 1997). Selective serotonin reuptake inhibitors (SSRIs) have been the most commonly reported antidepressant agents to cause bruxism and distress patients' lives (Winocur et al., 2003). The serotonin-norepinephrine reuptake inhibitor (SNRI) venlafaxine, but not duloxetine, has also been reported to be associated with bruxism in sporadic cases (Alonso-Navarro et al., 2009; Jaffee and Bostwick, 2000; Brown and Hong, 1999; Kuloglu et al., 2010). To our knowledge, there has been no report on relieving bruxism symptoms with an SNRI substitution.