Impact of short access nicotine self-administration on expression of alpha 4 beta 2*nicotinic acetylcholine receptors in non-human primates

摘要

Rationale Although nicotine exposure upregulates the alpha 4 beta 2* subtype of nicotinic acetylcholine receptors (nAChRs), the upregulation of nAChRs in non-human primates voluntarily self-administering nicotine has never been demonstrated.