Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice

Trigo Jose M.; Le Foll Bernard

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Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice

机译：抑制单酰基甘油脂肪酶（MAGL）增强提示诱导小鼠尼古丁寻找行为的恢复

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Rationale Tobacco smoking is still a major population health issue. The endocannabinoid system has been shown to control drug-seeking behaviors. There are two main endocannabinoids: anandamide degraded by fatty acid amide hydrolase (FAAH) and 2-arachidonoylglycerol (2-AG) degraded by monoacylglycerol lipase (MAGL).

机译：基本原理吸烟仍然是人口健康的主要问题。内源性大麻素系统已被证明可以控制药物寻找行为。有两种主要的内源性大麻素：被脂肪酸酰胺水解酶（FAAH）降解的anandamide和被单酰基甘油脂酶（MAGL）降解的2-花生四烯酰基甘油（2-AG）。

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《Psychopharmacology》 |2016年第10期|共8页
作者
Trigo Jose M.; Le Foll Bernard;
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正文语种 eng
中图分类药理学;
关键词
2-arachidonoylglycerol; Nicotine; Reinstatement; Self-administration; Mice;

机译：2-花生四烯酸甘油酯;尼古丁;恢复;自我给药;小鼠;

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专利

1. Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice [J] . Trigo Jose M., Le Foll Bernard Psychopharmacology . 2016,第10期

机译：抑制单酰基甘油脂肪酶（MAGL）增强提示诱导小鼠尼古丁寻找行为的恢复
2. A Role for Hypocretin|[sol]|Orexin Receptor-1 in Cue-Induced Reinstatement of Nicotine-Seeking Behavior [J] . Ainhoa Plaza-Zabala, áfrica Flores, Elena Martín-García, Neuropsychopharmacology . 2013,第9期

机译：Hypocretin | [sol] | Orexin Receptor-1在提示诱导的尼古丁寻找行为恢复中的作用
3. Acamprosate attenuates cue-induced reinstatement of nicotine-seeking behavior in rats. [J] . Pechnick RN, Manalo CM, Lacayo LM, Behavioural pharmacology . 2011,第3期

机译：阿坎酸可减弱提示诱导的大鼠尼古丁寻找行为的恢复。
4. Identifying the neuroanatomical substrate involved in ICVNPY inhibition of reinstatement of cocaine-induced behavior in rats by MALDI IMAGING [C] . Leila Shahri, Alexis C. Thomson, Troy D. Wood American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：用MALDI成像鉴定ICVNPY抑制依赖于可卡因诱导的行为的抑制的神经杀菌底物
5. Variants of Monoacylglycerol Lipase (MAGL) and an Assessment of a Spectrophotometric Assay for MAGL Activity [D] . Ulloa, Nadine Martina 2011

机译：单酰基甘油脂肪酶（MAGL）的变体和MAGL活性的分光光度法评估
6. Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice [O] . Carolina Costola-de-Souza, Alison Ribeiro, Viviane Ferraz-de-Paula, -1

机译：单酰基甘油脂肪酶（MAGL）抑制减轻小鼠的急性肺损伤。
7. Monoacylglycerol lipase (MAGL) inhibition attenuates acute lung injury in mice. [O] . Carolina Costola-de-Souza, Alison Ribeiro, Viviane Ferraz-de-Paula, 2013

机译：单酰基甘油脂肪酶（maGL）抑制减轻小鼠的急性肺损伤。

Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice

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