Temperature Dependence of Gas Chromatography Retention Indices As One of the Main Factors Determining Their Interlaboratory Reproducibility

摘要

Temperature dependence of gas chromatography retention indices should be considered one of the main sources of their interlaboratory irreproducibility. The regularities of this dependence for packed and capillary columns or individual compounds allow revealing and characterizing other factors affecting reproducibility of the indices. These include the ratio of amounts of target analytes and reference compounds, as well as their polarity. Considering the anomalies in temperature dependences of retention indices of polar compounds on nonpolar phases allows assuming that it can be one of the causes of the asymmetry of the sets of reference data.