Lipoxin analogs and lipoxin formation in vivo.

摘要

The definition of lipoxin bioactions in vivo and of lipoxin levels in humans, under physiological and pathological conditions, represents a main task toward the clinical use of lipoxins. The introduction of lipoxin stable analogs and of new methodology for immunological measurements of lipoxin A4 in human fluids is significantly contributing to fulfill this task. This chapter reviews the current literature on the use of lipoxin analogs, in vivo, and on measurements of lipoxin A4 in health and disease.