Electronic cigarette (EC) usage has increased exponentially, but limited data are available on its potential harmful effects. We tested for the presence of reactive, short-lived free radicals in EC aerosols by electron paramagnetic resonance spectroscopy (EPR) using the spin-trap phenyl-N-tert-butylnitrone (PBN). Radicals were detected in aerosols from all ECs and eliquids tested (2.5 X 10(13) to 10.3 X 10(13) radicals per puff at 3.3 V) and from eliquid solvents propylene glycol and glycerol and from "dry puffing". These results demonstrate, for the first time, the production of highly oxidizing free radicals from ECs which may present a potential toxicological risk to EC users.
展开▼
机译：电子烟（EC）的使用呈指数增长，但是有关其潜在有害影响的数据有限。我们使用自旋阱苯基-N-叔丁基硝酮（PBN）通过电子顺磁共振波谱（EPR）测试了EC气溶胶中反应性，短寿命自由基的存在。在所有EC和测试的液体中（在3.3 V下每抽吸一次，在2.5 X 10（13）至10.3 X 10（13）自由基中），在液体溶剂中丙二醇和甘油以及从“干膨化”中检测到自由基。这些结果首次证明了EC产生的高氧化性自由基可能对EC使用者造成潜在的毒理学风险。
展开▼
