PLURONIC MICELLES AS VEHICLES FOR THE TUMOR- SPECIFIC DELIVERY 01? TWO ANTI-CANCER DRUGS TO HL-60 CELLS USING ACOUSTIC ACTIVATION

摘要

Chemotherapy for localized tumor treatment often is administered systemically, which delivers the drugs throughout the body as well as to the target sites. One of the many disadvantages of systemic delivery is that the chemotherapeutic agents often produce unwanted side effects on healthy tissues or organs in the body. An ideal scenario would be to sequester the drug in a package that would have minimal interaction with the body, and would contain the drug until release; then at the appropriate time and place in the body the drug could be released from the sequestering container.