Characterization of particle size distribution of polymeric nanoparticles by packed column hydrodynamic chromatography

摘要

An extremely active and prolific field in modern polymer chemistry is finding ways to control size and morphology of colloids at the nanometer level. Commercial applications of such materials require accurate characterization of polymeric nanoparticles at both the R&D and production stages of a product's lifecycle. Measurement of particle size distribution in this size range can be very challenging, particularly if the size distribution is complex.