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首页> 外文期刊>Peptides: An International Journal >Sex differences in neuropeptide distribution in the rat brain.
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Sex differences in neuropeptide distribution in the rat brain.

机译:大鼠大脑中神经肽分布的性别差异。

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摘要

We have investigated possible sex differences in the regional concentrations of neuropeptides in the rat brain. Immunoreactive neurotensin (NT), neurokinin A (NKA), galanin (GAL), calcitonin gene-related peptide (CGRP), substance P (SP) and neuropeptide Y (NPY) were measured by radioimmunoassay in frontal cortex, occipital cortex, hippocampus, striatum, hypothalamus and pituitary in male and female pre- and postpubertal rats. Sex differences were found for NPY (p < 0.001), NT (p < 0.01) and GAL (p < 0.05), in particular in hippocampus, striatum, hypothalamus and pituitary, but not for CGRP, SP and NKA. Results from analysis of neuropeptides in one sex may not be entirely applicable to the other.
机译:我们研究了大鼠大脑中神经肽区域浓度的可能性别差异。通过放射免疫法测定额叶皮层,枕叶皮层,海马区的免疫反应性神经降压素(NT),神经激肽A(NKA),甘丙肽(GAL),降钙素基因相关肽(CGRP),P物质(SP)和神经肽Y(NPY)。雌性和青春期前后大鼠的纹状体,下丘脑和垂体。在NPY(p <0.001),NT(p <0.01)和GAL(p <0.05)中发现性别差异,特别是在海马,纹状体,下丘脑和垂体中,但CGRP,SP和NKA则没有。一种性别中神经肽的分析结果可能并不完全适用于另一种性别。

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