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The effects of neurotensin on selected parameters of lipid metabolism in rats.

机译:神经降压素对大鼠脂质代谢选择参数的影响。

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15 nM/kg b.m. of neurotensin (NT) caused a significant inhibition of LMA within 30 min of administration and this effect persisted up for to the 240 th minute of the experiment. A 15 nM/kgb.m. dose also caused a reduction in SLA which persisted up to the 120 th minute. Sixty minutes after an intraperitoneal administration of NT a decrease in the cholesterol and NEFA levels and an increase in the TG and glycerol levels were observed. These effects were inhibited by the NTR2-blocker (levocabastine) and were not subject to change after an in vivo application of SR 48692.
机译:15 nM / kg下午神经降压素(NT)的使用在给药后30分钟内对LMA产生了明显的抑制作用,这种作用持续到实验的第240分钟。 15 nM / kgb.m。剂量还会导致SLA降低,并持续至120分钟。腹膜内给予NT后60分钟,胆固醇和NEFA水平降低,TG和甘油水平升高。这些作用被NTR2受体阻滞剂(左旋卡巴汀)抑制,在体内应用SR 48692后不会发生变化。

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