Diphenylether and Macrotriolides Occurring in a Fungal Isolate from the Antarctic Lichen Neuropogon

摘要

The fungus,Tritirachium sp.HKI 0317,was isolated from the Antarctic lichen Neuropogon sp.Fermentation of this strain,extraction of the culture broth,and preparative separation of produced compounds furnished 4-carboxy-5,5'-dihydroxy-3,3'-dimethyldiphenylether,macrosphelide A,and macrosphelide J.The structures were elucidated on the basis of MS and NMR measurements,and the previously published data for this compounds.