Silver-Catalyzed Csp-H and Csp-Si Bond Transformations and Related Processes

摘要

Alkynes are extremely versatile unsaturated hydrocarbons,1 which are ubiquitously found in functional materials,2 supramolecules,3 and natural products.4 Further, they are also useful synthetic intermediates from which a wide variety of saturated and unsaturated compounds can be obtained via addition reactions across their C-C triple bonds.5 In particular, recent advances in the transition-metal-catalyzed transformations of alkynes have provided rapid and concise access to complex molecular architectures.6 Therefore, the development of a new preparative method of substituted alkynes promises to greatly expand the utility of the synthetic methodologies based on their transformations.