Synthesis, characterization, X-ray crystallography and antimicrobial activities of new Co(III) and Cu(II) complexes with a pyrazole based Schiff base ligand

摘要

A new pyrazole based 'NNS' tridentate ligand, 5-methylpyrazole-3yl-N-(20-methylthiophenyl)methyleneimine(MPzOATA), has been synthesized and characterized by elemental analyses, mass, IR and NMR spectroscopy. The versatile coordination mode of the ligand has been established with the synthesis of two metal-organic complexes with different metal ions, Co(III) (complex I) and Cu(II) (complex II). These metal-organic complexes have been characterized by single crystal X-ray structure analyses, along with several spectral techniques. Structural analyses of both the monomeric complexes reveal that complex I crystallized in the monoclinic C2/c space group, while complex II crystallized in the orthorhombic Pbca(#61) space group. In complex I, the Co(III) centre shows a six coordinate octahedral geometry, while in complex II, the Cu(II) centre shows a five coordinate square pyramidal geometry. The reported ligand and the metal ion complexes have been screened for their in vitro antimicrobial activity against some pathogenic bacteria.