Nano ZrP2O7 Catalyzed Multicomponent Reaction for an Easy Access of 4H-pyrans and 1,4-dihydropyridines

摘要

ZrP2O7 nanoparticle catalyzed one-pot synthesis of 4H-pyran scaffolds installing a one-pot three-component coupling reaction of an aldehyde, malononitrile, and ethyl acetoacetate. Also the synthesis of 1,4-dihydropyridines was investigated by using aldehydes, ethyl acetoacetate and ammonium acetate as utilizing nano structured ZrP2O7 as an efficient catalyst in ethanol. The attractive features of this process are mild reaction conditions, reusability of the catalyst, short reaction times, easy isolation of the products, and excellent yields.