Anti-inflammatory and Surgical Therapy of Olfactory Disorders Related to Sino-nasal Disease

摘要

Olfactory loss may be caused by mechanical obstructin or inflammation of the olfactory epithelium due to allergicon-allergic rhintis and hronic sinusitis with or without polyps. Treatment of olfactory loss related to spino-nasal disease is possible. Apart from surgical approaches and/or treatment with antibiotics, both systemic and topical steroids are effectively used in the therapy of olfactory loss related to sino-nasal disease. In most cases improvement of olfactory function appears to relate to the anti-inflammatory actions of the steroids used. While some details of therapeutic effect and dose regimen are not clear, systemic steroids are often helpful even in patients without nasal obstruction due to polyps or obvious inflammatory changes.