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Synthesis,Structure and Antibacterial Activities of Schiff Base Derived from PMBP with 2-Furfurylamine and Its Complexes

机译:含2-糠胺的PMBP席夫碱的合成,结构及抑菌活性

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摘要

4-Acyl-5-pyrazolone is a family of flexible beta-diketonate,which are widely used and well known for their applications as analgesics,antipyretics,anti-inflammatory and insecticides[1,2].Therefore,the studies of derivatives of 4-acyl-5-pyrazolone are the focus of many research groups working in the fields gf coordination chemistry,biomedicine and pharmaceutical chemistry[3].In order to extend our knowledge of 4-acyl-5-pyrazoIone,several Schiff bases derived from TTA[4,4,4-trifIuoro-l-(2-thie-nyl)-l,3-butanedione]were studied[4-6].In this communication the synthesis,structure and antibacterial activities of the title compounds are reported.
机译:4-酰基-5-吡唑啉酮是一类柔性的β-二酮酸酯,因其在镇痛药,退热药,抗炎药和杀虫剂中的应用而广为人知[1,2]。因此,对4的衍生物的研究-酰基-5-吡唑啉酮是配位化学,生物医学和药物化学领域的许多研究小组的重点[3]。为了扩展我们对4-酰基-5-吡唑啉酮的认识,衍生自TTA的几种席夫碱研究了[4,4,4-三氟-1-(2-噻吩基)-1,3-丁二酮] [4-6]。在该文献中,报道了标题化合物的合成,结构和抗菌活性。

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