Thermal,Spectral,Magnetic and Biological Studies of Thiosemicarbazones Complexes with Metal Ions:Cu(II),Co(II),Ni(II),Fe(III),Cd(II),Zn(II),Mn(II) and UO_2(VI)

摘要

Thiosemicarbazones ligands,isatin-3-thiosemicarbazone (HIT) and N-acetylisatin-3-thiosemicarbazone (HAIT),which have tridentate ONN coordinating sites were prepared.The complexes of both ligands with Cu(II),Co(II),Ni(II),Fe(III),Cd(II),Zn(II),Mn(II) and UO_2(VI) ions were isolated.The ligands and their metal complexes were characterized by elemental analyses,IR,UV-Vis and mass spectra,also by conductance,magnetic moment and TG-DSC measurements.All the transition metal complexes have octahedral configurations,except Cu-complexes,which were found to have the square-planar geometry and the UO_2( VI) complexes which have coordination number 8 and may acquire the distorted dodecahedral geometry.Thermal studies explored the possibility of obtaining new complexes.Inversion from octahedral to square-planar configuration occurred upon heating the parent Ni-HAIT complex to form the corresponding pyrolytic product.The antifungal activity against the tested organisms showed that some metal complexes enhanced the activity with respect to the parent ligands.