Synthesis and Properties of a Trinuclear Copper(II) Complex with Trithiocyanurate Bridge

摘要

Mixed-ligand trinuclear Cu(II) complex involving trithiocyanurate(3-) anion (ttc3-) and N,N,N',N",N"-pentamethyldiethylenetriamine (pmdien) in the coordination sphere of composition [Cu3(pmdien)3(mu-ttc)](ClO4)3 has been prepared.The complex has been characterized by EA,IR,UV-Vis,and mass spectroscopy.We can assume,that the complex is trinuclear with central atoms connected by trithiocyanurate(3-) bridges.Each central atom is in deformed trigonal bypiramidal arrangement formed by chelating S,N atoms of ttc(3-) and by three N atoms of pmdien.Temperature dependence of magnetic susceptibility and EPR spectroscopy have also been employed to characterize the compound.Magnetic susceptibility measurements over the 1.8-300 K temperature range revealed antiferromagnetic interactions among central atoms.The antitumor activity in vitro against G-361 (human malignant melanoma),HOS (human osteogenic sarcoma),K-562 (human chronic myelogenous leukaemia) and MCF-7 (human breast adenocarcinoma) tumor cell lines have been tested but unfortunately the complexes showed no cytotoxic activity against the four cell lines.