Patient-specific estimates of vascular and placental properties in growth-restricted fetuses based on a model of the fetal circulation

摘要

Introduction: Intrauterine growth restriction (IUGR) due to placental insufficiency is associated with blood-flow redistribution in order to maintain perfusion to the brain. However, some hemodynamic parameters that might be more directly related to staging of the disease cannot be measured noninvasively in clinical practice. For this, we developed a patient-specific model of the fetal circulation to estimate vascular properties of each individual.