Pharmacokinetics and pharmacodynamics of glycyrrhetinic acid with Paeoniflorin after transdermal administration in dysmenorrhea model mice

Ding Xue; Sun Yuming; Wang Qing; Pu Tingting; Li Xiaohui; Pan Yaqing; Yang Yang

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Pharmacokinetics and pharmacodynamics of glycyrrhetinic acid with Paeoniflorin after transdermal administration in dysmenorrhea model mice

机译：痛经模型小鼠经皮给药后甘草次酸和Pa药苷的药代动力学和药效学

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Background: Glycyrrhetinic acid (GA) and paeoniflorin (PF) are the main active ingredients in Chinese peony-Liquorice Decoction, a widely used Traditional Chinese Medicine.

机译：背景：甘草次酸（GA）和pa药苷（PF）是牡丹-甘草汤（一种广泛使用的中药）的主要活性成分。

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来源
《Phytomedicine :》 |2016年第8期|共8页
作者
Ding Xue; Sun Yuming; Wang Qing; Pu Tingting; Li Xiaohui; Pan Yaqing; Yang Yang;
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正文语种 eng
中图分类植物学;
关键词
Glycyrrhetinic acid; Paeoniflorin; Pharmacokinetics; Pharmacodynamics; Analgesic; Transdermal drug delivery;

机译：甘草次酸;Pa药苷;药代动力学;药效学;镇痛;透皮给药;

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1. Pharmacokinetics and pharmacodynamics of glycyrrhetinic acid with Paeoniflorin after transdermal administration in dysmenorrhea model mice [J] . Ding Xue, Sun Yuming, Wang Qing, Phytomedicine : . 2016,第8期

机译：痛经模型小鼠经皮给药后甘草次酸和Pa药苷的药代动力学和药效学
2. Physiologically based pharmacokinetic-pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans [J] . Kong Wei-min, Sun Bin-bin, Wang Zhong-jian, International journal of sports medicine . 2020,第6期

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3. Physiologically based pharmacokinetic-pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans [J] . Wei-min Kong, Ru-jun Xu, Ping Li, 中国药理学报：英文版 . 2020,第006期
4. Solid-phase exaction-liquid chromatographic method for the determination and pharmacokinetic studies of albiflorin and paeoniflorin in rat serum after oral administration of Si-Wu decoction [C] . 北京大学中医药现代研究中心2004年年会论文集 . 2005

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Pharmacokinetics and pharmacodynamics of glycyrrhetinic acid with Paeoniflorin after transdermal administration in dysmenorrhea model mice

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