28.
Inhibition of sphingosine 1-phosphate lyase for the treatment of rheumatoid arthritis: Discovery of (E)-1-(4-((1 R,2 S,3 R)-1,2,3,4-tetrahydroxybutyl)-1 H -imidazol-2-yl)ethanone oxime (LX2931) and (1 R,2 S,3 R)-1-(2-(Isoxazol-3-yl)-1 H -imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)
机译:抑制鞘氨醇1-磷酸裂合酶治疗类风湿关节炎:(E)-1-(4-((1 R,2 S,3 R)-1,2,3,4-四羟基丁基)-1 H的发现-咪唑-2-基)乙酮肟(LX2931)和(1 R,2 S,3 R)-1-(2-(异恶唑-3-基)-1 H-咪唑-4-基)丁烷-1, 2,3,4-四醇(LX2932)