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Genes and Diseases

中文名称：基因与疾病

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1.Forskolin and Phorbol 12-myristate 13-acetate modulates the expression pattern of AP-1 factors and cell cycle regulators in estrogen-responsive MCF-7?cells

机译：Forskolin和Phorbol 12-肉豆蔻酸酯13-乙酸酯调节雌激素反应性MCF-7？细胞中AP-1因子和细胞周期调节剂的表达模式
- 作者：R.L. Babu;M. Naveen Kumar;Rajeshwari H. Patil;K.M. Kiran Kumar;K.S. Devaraju;Govindarajan T. Ramesh;S. Chidananda Sharma
- 期刊名称：《Genes and Diseases》 | 2019年第2期
- AP-1 transcription factorCell cycleForskolinMCF-7 cellsPhorbol esters;
2.Integrated transcriptome interactome study of oncogenes and tumor suppressor genes in breast cancer

机译：乳腺癌中癌基因和抑癌基因的转录组相互作用组研究
- 作者：G. Pranavathiyani;Raja Rajeswary Thanmalagan;Naorem Leimarembi Devi;Amouda Venkatesan
- 期刊名称：《Genes and Diseases》 | 2019年第1期
- Breast cancerDifferential gene expressionNetwork analysisOncogenesTumor suppressor genes;
3.Structural investigation of Rett-inducing MeCP2 mutations

机译：Rett诱导MeCP2突变的结构研究
- 作者：Ottavia Spiga;Simone Gardini;Nicole Rossi;Vittoria Cicaloni;Francesco Pettini;Neri Niccolai;Annalisa Santucci
- 期刊名称：《Genes and Diseases》 | 2019年第1期
- DNA binding domainsMeCP2Mutation distributionProtein structureRett syndrome;
4.PRMT5 in gene regulation and hematologic malignancies

机译：PRMT5在基因调控和血液系统恶性肿瘤中的作用
- 作者：Fen Zhu;Lixin Rui
- 期刊名称：《Genes and Diseases》 | 2019年第3期
- Gene regulationHematologic malignanciesMetabolismPathogenesisPRMT5;
5.Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins (BMPs) in lineage commitment and differentiation of mesenchymal stem cells (MSCs)

机译：14种骨形态发生蛋白（BMP）在间充质干细胞（MSC）的谱系定型和分化中调控转录组景观
- 作者：Linghuan Zhang;Qing Luo;Yi Shu;Zongyue Zeng;Bo Huang;Yixiao Feng;Bo Zhang;Xi Wang;Yan Lei;Zhenyu Ye;Ling Zhao;Daigui Cao;Lijuan Yang;Xian Chen;Bin Liu;William Wagstaff;Russell R. Reid;Hue H. Luu;Rex C. Haydon;Michael J. Lee
- 期刊名称：《Genes and Diseases》 | 2019年第3期
- Bone morphogenetic proteins (BMPs)MAP kinase signalingMesenchymal stem cellsNotch signalingPI3K/AKT/mTOR pathwaySmad signalingTGFβ superfamilyWnt signaling;
6.Writing and erasing MYC ubiquitination and SUMOylation

机译：编写和擦除MYC泛素化和SUMOylation
- 作者：Yingxiao Chen;Xiao-Xin Sun;Rosalie C. Sears;Mu-Shui Dai
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- deSUMOylating enzymesDeubiquitinating enzymesMYCSUMOSUMOylationUbiquitination;
7.Regulation of the Hippo signaling pathway by deubiquitinating enzymes in cancer

机译：癌症中去泛素化酶对河马信号通路的调控
- 作者：Ashley Mussell;Costa Frangou;Jianmin Zhang
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- CancerDeubiquitinaseHippo signaling pathwayUbiquitinaseYAP/TAZ;
8.A novel inhibitor of MDM2 oncogene blocks metastasis of hepatocellular carcinoma and overcomes chemoresistance

机译：新型MDM2癌基因抑制剂可阻止肝细胞癌转移并克服化学耐药性
- 作者：Wei Wang;Bo Hu;Jiang-Jiang Qin;Jian-Wen Cheng;Xin Li;Mehrdad Rajaei;Jia Fan;Xin-Rong Yang;Ruiwen Zhang
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- CRISPR/Cas9Hepatocellular carcinomaMDM2p53-independentPatient-derived xenograft;
9.Paradox-driven adventures in the development of cancer immunology and immunotherapy

机译：悖论驱动的癌症免疫学和免疫疗法发展历程
- 作者：Whitney Barham;Joanina K. Gicobi;Yiyi Yan;Roxana S. Dronca;Haidong Dong
- 期刊名称：《Genes and Diseases》 | 2019年第3期
- BiomarkerCancer immunotherapyCytotoxic T cellsHyperprogressionImmune checkpointsPD-L1PD-1;
10.SKA2/FAM33A: A novel gene implicated in cell cycle, tumorigenesis, and psychiatric disorders

机译：SKA2 / FAM33A：与细胞周期，肿瘤发生和精神疾病有关的新基因
- 作者：Mengyu Xie;Youquan Bu
- 期刊名称：《Genes and Diseases》 | 2019年第1期
- SKA2FAM33ACell cycleTumorGene expression regulationDNA methylation;
11.Maternal vitamin D level and vitamin D receptor gene polymorphism as a risk factor for congenital heart diseases in offspring; An Egyptian case-control study

机译：母亲维生素D水平和维生素D受体基因多态性是后代先天性心脏病的危险因素;埃及病例对照研究
- 作者：Wesam A. Mokhtar;Amal Fawzy;Reem M. Allam;Rania M. Amer;Mona S. Hamed
- 期刊名称：《Genes and Diseases》 | 2019年第2期
- Congenital heart diseaseFoK1 polymorphismVitamin DVitamin D receptor geneMaternal vitamin D;
12.Do specific ultrasonography features identified at the time of early pregnancy loss predict fetal chromosomal abnormality? – A systematic review and meta-analysis

机译：妊娠早期流产时识别出的特定超声检查特征是否可以预测胎儿染色体异常？ –系统的审查和荟萃分析
- 作者：J. Huang;W. Zhu;J. Tang;S.H. Saravelos;L.C.Y. Poon;T.C. Li
- 期刊名称：《Genes and Diseases》 | 2019年第2期
- UltrasonographyEarly pregnancy lossChromosomal abnormalityPredictive value;
13.Endosomal trafficking defects in patient cells with KIAA1109 biallelic variants

机译：具有KIAA1109双等位基因变体的患者细胞中的内体运输缺陷
- 作者：Megan S. Kane;Callie J. Diamonstein;Natalie Hauser;John F. Deeken;John E. Niederhuber;Thierry Vilboux
- 期刊名称：《Genes and Diseases》 | 2019年第1期
- CiliaEndocytosisKIAA1109Neurological malformationVesicular trafficking;
14.Evaluation on monoamine neurotransmitters changes in depression rats given with sertraline, meloxicam or/and caffeic acid

机译：舍曲林，美洛昔康或/和咖啡酸对抑郁大鼠单胺神经递质变化的评估
- 作者：Dan Huang;Lu Zhang;Jun-qing Yang;Ying Luo;Ting Cui;Ting-ting Du;Xin-hui Jiang
- 期刊名称：《Genes and Diseases》 | 2019年第2期
- AA-COX-2/5-LO inflammatory pathwaysBioamine neurotransmittersCaffeic acidDepression ratMeloxicamSertraline;
15.Emergence of antibiotic resistance Pseudomonas aeruginosa in intensive care unit; a critical review

机译：重症监护病房出现铜绿假单胞菌对抗生素的耐药性;批判性评论
- 作者：Preeti Pachori;Ragini Gothalwal;Puneet Gandhi
- 期刊名称：《Genes and Diseases》 | 2019年第2期
- AntibioticsBlood stream infectionsInfectionPathogenResistanceUrinary tract infections;
16.Role of rno-miR-124-3p in regulating MCT1 expression in rat brain after permanent focal cerebral ischemia

机译：rno-miR-124-3p在调节永久性局灶性脑缺血后大鼠脑中MCT1表达中的作用
- 作者：Shi-ye Xu;Xu-li Jiang;Qian Liu;Jin Xu;Juan Huang;Sheng-wei Gan;Wei-tian Lu;Fei Zhuo;Mei Yang;Shan-quan Sun
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- Cerebral ischemiaLactate acidMonocarboxylate transporters (MCTs)microRNAs (miRNAs)Permanent middle cerebral artery occlusion (pMCAO);
17.The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine

机译：BMP9的奇迹：从间充质干细胞分化，血管生成，神经发生，肿瘤发生，代谢到再生医学
- 作者：Sami Mostafa;Mikhail Pakvasa;Elam Coalson;Allen Zhu;Alex Alverdy;Hector Castillo;Jiaming Fan;Alex Li;Yixiao Feng;Di Wu;Elliott Bishop;Scott Du;Mia Spezia;Alissa Li;Ofir Hagag;Alison Deng;Winny Liu;Mingyang Li;Sherwin S. Ho;Aravind Athiviraham
- 期刊名称：《Genes and Diseases》 | 2019年第3期
- AdipogenesisBone morphogenetic proteins (BMPs)BMP9/GDF2Mesenchymal stem cells (MSCs)MetabolismOsteogenesisRegenerative medicineTumorigenesis;
18.Decreased osteogenic activity and mineralization of alveolar bone cells from a patient with amelogenesis imperfecta and FAM83H 1261GT mutation

机译：牙釉质发育不全和FAM83H 1261G> T突变患者的牙槽骨细胞成骨活性和矿化降低
- 作者：Nunthawan Nowwarote;Thanaphum Osathanon;Kiattipan Kanjana;Thanakorn Theerapanon;Thantrira Porntaveetus;Vorasuk Shotelersuk
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- Autosomal dominant inheritanceEnamel hypoplasiaHypocalcified enamelMineralizationOsteogenic differentiationPeriodontium;
19.Oxygen sensing and adaptability won the 2019 Nobel Prize in Physiology or medicine

机译：氧气感应和适应性荣获2019年诺贝尔生理学或医学奖
- 作者：Qing Zhang;Qin Yan;Haifeng Yang;Wenyi Wei
- 期刊名称：《Genes and Diseases》 | 2019年第4期
20.Stem cell therapy for chronic skin wounds in the era of personalized medicine: From bench to bedside

机译：个性化医学时代的干细胞治疗慢性皮肤伤口：从长凳到床边
- 作者：Elam Coalson;Elliot Bishop;Wei Liu;Yixiao Feng;Mia Spezia;Bo Liu;Yi Shen;Di Wu;Scott Du;Alexander J. Li;Zhenyu Ye;Ling Zhao;Daigui Cao;Alissa Li;Ofir Hagag;Alison Deng;Winny Liu;Mingyang Li;Rex C. Haydon;Lewis Shi
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- Chronic inflammationChronic woundsGrowth factorsPersonalized medicineSkinStem cellsWound healing;
21.Identification and characterization of the cellular subclones that contribute to the pathogenesis of mantle cell lymphoma

机译：鉴定和表征有助于套细胞淋巴瘤发病的细胞亚克隆
- 作者：Junling Tang;Li Zhang;Tiejun Zhou;Zhiwei Sun;Liangsheng Kong;Li Jing;Hongyun Xing;Hongyan Wu;Yongli Liu;Shixia Zhou;Jingyuan Li;Mei Chen;Fang Xu;Jirui Tang;Tao Ma;Min Hu;Dan Liu;Jing Guo;Xiaofeng Zhu;Yan Chen
- 期刊名称：《Genes and Diseases》 | 2019年第4期
- JeKo-1-spheroidMantle cell lymphomaPathologySub-cloneCD19;
22.Effect of the electro-acupuncture on senile plaques and its formation in APP+/PS1+ double transgenic mice

机译：电针对APP + / PS1 +双转基因小鼠老年斑的形成及其影响
- 作者：Qinghua Yang;Shujuan Zhu;Jin Xu;Chenglin Tang;Kaihui Wu;Yanjun Wu;Yiying Wang;Huajun Sheng
- 期刊名称：《Genes and Diseases》 | 2019年第3期
- Alzheimer's diseaseAmyloid β-proteinElectro-acupunctureSenile plaquesTransgenic miceAD Alzheimer's diseaseAβ amyloid β-proteinSPs senile plaquesAPP β－amyloid precursor protein BACE1β－ site APP cleavageIDE insulin degrading enzymeEA electro-acupunctureIHC immunohistochemistrySOD superoxide dismutaseAch aetylcholineChAT aetylcholine tansferaseAchE cholinesterase;
23.Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq

机译：RNA-SEQ检测到的肝细胞癌细胞中PCK1过表达的转录组变化
- 作者：Jin Xiang;Yuhong Zhang;Lin Tuo;Rui Liu;Dongmei Gou;Li Liang;Chang Chen;Jie Xia;Ni Tang;Kai Wang
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Hepatocellular carcinoma cellsOncogenePhosphoenolpyruvate carboxylase kinase1 (PCK1)RNA sequencingWnt signaling pathway;
24.Three-dimensional printed tissue engineered bone for canine mandibular defects

机译：用于甘蓝颌骨缺陷的三维印刷组织工程骨骼
- 作者：Li Zhang;Junling Tang;Libo Sun;Ting Zheng;Xianzhi Pu;Yue Chen;Kai Yang
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Mandibular defectTissue engineering bone3D printingCAD/CAMBMSCs;
25.Gene therapy and genome editing for primary immunodeficiency diseases

机译：基因治疗与原发性免疫缺陷疾病的基因组编辑
- 作者：Zhi-Yong Zhang;Adrian J. Thrasher;Fang Zhang
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Adenosine deaminase deficientChronic granulomatous diseaseGene therapyGenome editingHematopoietic progenitor stem cellsPrimary immunodeficiency diseasesWiskott-Aldrich syndromeX-liked severe combined immunodeficiency;
26.Recent advances in chronic granulomatous disease

机译：慢性肉芽肿疾病最近的进展
- 作者：Gummadi Anjani;Pandiarajan Vignesh;Vibhu Joshi;Jitendra Kumar Shandilya;Dharmagat Bhattarai;Jyoti Sharma;Amit Rawat
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Chronic granulomatous diseaseColitisEROSGeneticsInfectionsInflammationp40phox;
27.An update on the genetics and pathogenesis of hereditary angioedema

机译：关于遗传性血统血管血管遗传学和发病机制的最新情况
- 作者：Aaqib Zaffar Banday;Anit Kaur;Ankur Kumar Jindal;Amit Rawat;Surjit Singh
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Angiopoietin 1C1 inhibitorFactor XIIGeneticsHereditary angioedemaPlasminogen;
28.Genetics of severe combined immunodeficiency

机译：严重联合免疫缺陷的遗传学
- 作者：Rajni Kumrah;Pandiarajan Vignesh;Pratap Patra;Ankita Singh;Gummadi Anjani;Poonam Saini;Madhubala Sharma;Anit Kaur;Amit Rawat
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Adenosine deaminaseFlow cytometryGeneticsNewborn screeningSevere combined immunodeficiency;
29.Leukocyte adhesion defect: Where do we stand circa 2019?

机译：白细胞粘附缺陷：我们在哪里立场2019年？
- 作者：Jhumki Das;Avinash Sharma;Ankur Jindal;Vaishali Aggarwal;Amit Rawat
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Neutrophilic defectNeutrophilic leukocytosisPhagocyte rollingPhagocytesPrimary immunodeficiency disorders;
30.Platelets in Kawasaki disease: Is this only a numbers game or something beyond?

机译：川崎病的血小板：这只是一个数字游戏还是超越的东西？
- 作者：Kanika Arora;Sandesh Guleria;Ankur Kumar Jindal;Amit Rawat;Surjit Singh
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- AspirinCD40 ligandKawasaki diseasePlatelet derived microparticlesPlateletsThrombosis;
31.Current status and prospects of primary immunodeficiency diseases in Asia

机译：亚洲初级免疫缺陷疾病的现状及前景
- 作者：Rakesh Kumar Pilania;Himanshi Chaudhary;Ankur Kumar Jindal;Amit Rawat;Surjit Singh
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- AsiaGenetic diagnosisHematopoietic stem cell transplantIntravenous immunoglobulinPrimary immunodeficiency diseases;
32.Recent advances in elucidating the genetics of common variable immunodeficiency

机译：阐明澄清常见可变免疫缺陷遗传学的最新进展
- 作者：Vaishali Aggarwal;Aaqib Zaffar Banday;Ankur Kumar Jindal;Jhumki Das;Amit Rawat
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Common variable immunodeficiency (CVID)EpigenomeGeneticsNext generation sequencing (NGS)Transcriptome;
33.An updated review on activated PI3 kinase delta syndrome (APDS)

机译：关于激活的PI3激酶三角曲面综合征（APDS）的更新综述
- 作者：Ankita Singh;Vibhu Joshi;Ankur Kumar Jindal;Babu Mathew;Amit Rawat
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Activated phosphoinositide 3-kinase δ syndrome (APDS)Gain of functionImmunodeficiencyLymphadenopathyLymphoproliferationp110δ-activating mutation causing senescent T cells;
34.Genetics on early onset inflammatory bowel disease: An update

机译：早期发病炎症肠病的遗传学：更新
- 作者：Johnson Nameirakpam;Rashmi Rikhi;Sanjay Singh Rawat;Jyoti Sharma;Deepti Suri
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Il-10 signalling defectIPEXNext generation sequencingTargeted therapyVery early onset inflammatory bowel disease;
35.An updated review on phenocopies of primary immunodeficiency diseases

机译：关于原发性免疫缺陷疾病的苯特征的最新综述
- 作者：Ankita Singh;Ankur K. Jindal;Vibhu Joshi;Gummadi Anjani;Amit Rawat
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Anti-cytokine antibodiesPhenocopiesPrimary immunodeficiency diseasesSomatic mutations;
36.Clinical phenotype of a Chinese patient with RIPK1 deficiency due to novel mutation

机译：新型突变引起的中国患者中国患者的临床表型
- 作者：Li Lin;Ying Wang;Luyao Liu;Wenjing Ying;Wenjie Wang;Bijun Sun;Jinqiao Sun;Xiaochuan Wang
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Combined immunodeficiencyInflammatory bowel diseaseMutationRIPK1;
37.Selective immunoglobulin A deficiency (SIgAD) primarily leads to recurrent infections and autoimmune diseases: A retrospective study of Chinese patients in the past 40 years

机译：选择性免疫球蛋白A缺乏（SIGAD）主要导致复发感染和自身免疫疾病：过去40年来中国患者的回顾性研究
- 作者：Wei Wang;Tianhao Yao;Tianyi Zhang;Meiying Quan;Changyan Wang;Chen Wang;Lejia Zhang;Xiaoyan Tang;Shan Jian;Hongmei Song
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Autoimmune diseasesChineseClinical manifestationsRecurrent infectionsSelective Immunoglobulin A Deficiency (SigAD);
38.The number and cytotoxicity and the expression of cytotoxicity-related molecules in peripheral natural killer (NK) cells do not predict the repeated implantation failure (RIF) for the in?vitro fertilization patients

机译：周围自然杀伤剂（NK）细胞中细胞毒性相关分子的数量和细胞毒性和表达不能预测in in in？体外施肥患者的重复植入衰竭（RIF）
- 作者：Hongzhan Zhang;Chunyu Huang;Xian Chen;Longfei Li;Su Liu;Yuye Li;Yongnu Zhang;Yong Zeng;Lina Hu
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Activating receptorInhibitory receptorNK cytotoxicityPeripheral blood NK cellsRepeated implantation failure;
39.ARHGEF38 as a novel biomarker to predict aggressive prostate cancer

机译：Arhgef38作为一种新的生物标志物，预测侵袭性前列腺癌
- 作者：Kun Liu;Aixiang Wang;Longke Ran;Wanfeng Zhang;Song Jing;Yujing Wang;Xianqin Zhang;Geli Liu;Wang Sen;Fangzhou Song
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Gleason scoreImmunohistochemistryKaplan–Meier survivalPCa;
40.The study on the safety and efficacy of amnion graft for preventing the recurrence of moderate to severe intrauterine adhesions

机译：羊膜腹移植治疗中度至重度宫内粘连复发的安全性和疗效研究
- 作者：Changjiang Li;Aiqi Cai;Congcong Sun;Benyuan Wu;Xinpei Chen;Yanhua Mao;Yingfeng Zhang;Yating Gou;Jie Yu;Yuhan Wang;Huanhuan Yu;Jia Wang
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Amnion graftAsherman's syndromeIntrauterine adhesionsRecurrence of adhesionTranscervical resection of adhesion;
41.Microvesicles (MIVs) secreted from adipose-derived stem cells (ADSCs) contain multiple microRNAs and promote the migration and invasion of endothelial cells

机译：从脂肪衍生的干细胞（ADSCs）分泌的微泡（MIV）含有多个MicroRNA，促进内皮细胞的迁移和侵袭
- 作者：Bo Huang;Lin-Feng Huang;Ling Zhao;Zongyue Zeng;Xi Wang;Daigui Cao;Lijuan Yang;Zhenyu Ye;Xian Chen;Bin Liu;Tong-Chuan He;Xiaozhong Wang
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Adipose-derived stem cells (ADSCs)AngiogenesisLet-7microRNAMicrovesicle (MIV);
42.Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARγ/NF-κB/IL-6 signaling pathway

机译：Pioglitazone通过PPARγ/ NF-κB/ IL-6信号通路进行创伤性脑损伤后改善神经元损伤
- 作者：Yongbing Deng;Xue Jiang;Xiaoyan Deng;Hong Chen;Jie Xu;Zhaosi Zhang;Geli Liu;Zhu Yong;Chengfu Yuan;Xiaochuan Sun;Changdong Wang
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Traumatic brain injuryIL-6PioglitazonePPARγp-NF-κB;
43.High-throughput 16S rDNA sequencing of the pulmonary microbiome of rats with allergic asthma

机译：大鼠肺部微生物的高通量16S RDNA测序过敏性哮喘
- 作者：Yang Xiong;Sen Hu;Hongyao Zhou;Hui Zeng;Xuan He;Dongni Huang;Xiaoyu Li
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- 16S rDNAAllergic asthmaIllumina sequencingPulmonary microbiomeRats;
44.The effects of repeated propofol anesthesia on spatial memory and long-term potentiation in infant rats under hypoxic conditions

机译：反复异丙酚麻醉对缺氧条件下婴幼儿大鼠空间记忆和长期增强的影响
- 作者：Mang Sun;Ruixue Yuan;Hui Liu;Jing Zhang;Shengfen Tu
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- AnesthesiaApoptosisHypoxemiaLTPPropofolSpatial memory;
45.Metabolic reprogram associated with epithelial-mesenchymal transition in tumor progression and metastasis

机译：与肿瘤进展和转移中的上皮 - 间充质转变相关的代谢重新编程
- 作者：Yifan Wang;Chenfang Dong;Binhua P. Zhou
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- EpigeneticsEpithelial-mesenchymal transitionHeterogeneityMetabolismPlasticity;
46.Enzymatic and metabolic regulation of lysine succinylation

机译：赖氨酸琥珀酰化的酶促和代谢调节
- 作者：Annapoorna Sreedhar;Elizabeth K. Wiese;Taro Hitosugi
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Lysine succinylationMetabolismPost-translational modificationSIRT5Succinyl-CoA;
47.RISC assembly and post-transcriptional gene regulation in Hepatocellular Carcinoma

机译：肝细胞癌中的RISC组装和转录后基因调控
- 作者：Prasanna K. Santhekadur;Divya P. Kumar
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- InflammationmiRNAOncogenesRegulationTumor suppressor genes;
48.Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism

机译：产后小鼠肝脏和肺部的高度表达BMP9 / GDF2可能考虑其对干细胞分化，血管生成，肿瘤生长和代谢的脂肪效应
- 作者：Wei Liu;Zhongliang Deng;Zongyue Zeng;Jiaming Fan;Yixiao Feng;Xi Wang;Daigui Cao;Bo Zhang;Lijuan Yang;Bin Liu;Mikhail Pakvasa;William Wagstaff;Xiaoxing Wu;Huaxiu Luo;Jing Zhang;Meng Zhang;Fang He;Yukun Mao;Huiming Ding;Yongtao Zhang
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- BMP9/GDF2Bone morphogenetic proteins (BMPs)Hepatic metabolismMesenchymal stem cellsNeurogenesisOsteogenic differentiationPulmonary arterial hypertensionTumorigenesis;
49.Metabolic reprogramming in tumors: Contributions of the tumor microenvironment

机译：肿瘤中的代谢重编程：肿瘤微环境的贡献
- 作者：Andrew N. Lane;Richard M. Higashi;Teresa W-M. Fan
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Cancer metabolismNutrient supplyStable isotope resolved metabolomicsTumor microenvironmentMetabolic fluxACO1,2 aconitase 1,2CP-MAS Cross polarization Magic Angle SpinningDMEM Dulbeccos Modified Eagles MediumECAR extracellular acidification rateECM extracellular matrixEMP Embden-Meyerhof PathwayIDH1,2 isocitrate dehydrogenase 1,2 (NADPltsupgt+lt/supgtdependent)IF interstitial fluid2OG 2-oxoglutarateME malic enzymeRPMI Roswell Park Memorial InstituteSIRM Stable Isotope Resolved MetabolomicsTIL tumor infiltrating lymphocyteTIM/TPI triose phosphate isomeraseTME Tumor Micro Environment;
50.Novel biallelic TRNT1 mutations lead to atypical SIFD and multiple immune defects

机译：新的双胞胎Trnt1突变导致非典型SIFD和多种免疫缺陷
- 作者：Lu Yang;Xiuhong Xue;Ting Zeng;Xuemei Chen;Qin Zhao;Xuemei Tang;Jun Yang;Yunfei An;Xiaodong Zhao
- 期刊名称：《Genes and Diseases》 | 2020年第1期
- Mild phenotypeMultiple immune defectsNovel mutationsSIFDTRNT1;
51.CNTs mediated CD44 targeting; a paradigm shift in drug delivery for breast cancer

机译：CNT介导的CD44靶向;乳腺癌药物递送的范式转变
- 作者：Nidhi Jain Singhai;Suman Ramteke
- 期刊名称：《Genes and Diseases》 | 2020年第2期
- Anti-cancerous therapyBreast cancerCD44DeliveryDrugMultiwalled carbon nanotubesSWCNTs Single-walled Carbon NanotubesMWCNTs Multiwalled Carbon NanotubesCD 44 Cluster of DifferentiationHA hyaluronic acidBBB Blood–Brain BarriersiRNA Small Interfering RNADNA Deoxyribonucleic acidMMPs Matrix metalloproteinaseHNSCC Head and neck squamous cell carcinomaPTT Photothermal TherapyPDT Photodynamic Therapy;
52.Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells

机译：化学疗法对肿瘤细胞侵袭和转移的不利影响
- 作者：Wei Xiong;Yong Liao;Ji-Yong Qin;Wen-Hui Li;Zhao-You Tang
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Biological behaviorCancerChemoradiotherapyMechanismInvasion and metastasis;
53.Whole-exome mutational landscape of metastasis in patient-derived hepatocellular carcinoma cells

机译：患者衍生肝细胞癌细胞中转移的全极端突变景观
- 作者：Qian Zhou;Zuli Li;Linlan Song;Di Mu;Jin Wang;Li Tian;Yong Liao
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Clonal evolutionEncyclopedia of genes and genomes (KEGG)Gene ontology (GO)Genome-wide associationHepatocellular carcinomaMetastatic potentialitySomatic gene mutationWhole exome sequencingbZIP basic-region leucine zipperBTB Broad-complex, Tramtrack, and Bric-a-bracCDS coding for amino acids in proteinCNC cap’n’collarCTR C-terminal regionCUL3 Cullin3DGR DC domain harboring six Kelch-repeat domainFA fatty acidGO Gene OntologyHCC hepatocellular carcinomaIVR intervening regionKEGG Kyoto Encyclopedia of Genes and GenomesNTR N-terminal regionOS overall survivalSNP single nucleotide polymorphismWES whole exome sequencing;
54.Amino acid variation analysis of surface spike glycoprotein at 614 in SARS-CoV-2 strains

机译：SARS-COV-2菌株614时表面棘皮糖苷氨基酸变异分析
- 作者：Canhui Cao;Liang Huang;Kui Liu;Ke Ma;Yuan Tian;Yu Qin;Haiyin Sun;Wencheng Ding;Lingli Gui;Peng Wu
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- ACE2COVID-19Phylogenetic treeSARS-CoV-2Surface spike glycoprotein;
55.Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

机译：2019年（Covid-19）：细胞因子风暴，超炎症表型和急性呼吸窘迫综合征
- 作者：Shi-hui Lin;Yi-si Zhao;Dai-xing Zhou;Fa-chun Zhou;Fang Xu
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Acute respiratory distress syndromeCOVID-19Cytokine stormHyper-inflammatory host responseSARS-CoV-2;
56.Pandemic COVID-19: Current status and challenges of antiviral therapies

机译：大流行covid-19：抗病毒疗法的现状和挑战
- 作者：Winglam Chan;Betsy He;Xiong Wang;Ming-Liang He
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- ChloroquineConvalescent plasma therapyCOVID-19HydroxychloroquineIvermectinNatural killer cell therapyRemdesivirSARS-CoV-2;
57.Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2

机译：基于细胞的伪病毒进入测定的研制以鉴定潜在的病毒进入抑制剂和对SARS-COV-2的中和抗体
- 作者：Jie Hu;Qingzhu Gao;Changlong He;Ailong Huang;Ni Tang;Kai Wang
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Antiviral therapeuticsCoronavirusNeutralizing antibodiesPseudovirusSARS-CoV-2Spike protein;
58.The clinical and immunological features of pediatric COVID-19 patients in China

机译：中国儿科Covid-19患者的临床和免疫功能
- 作者：Juan Chen;Zhen-Zhen Zhang;Yao-Kai Chen;Quan-Xin Long;Wen-Guang Tian;Hai-Jun Deng;Jie-Li Hu;Xian-Xiang Zhang;Pu-Liao;Jiang-Lin Xiang;Dao-Xin Wang;Peng Hu;Fa-Chun Zhou;Zhi-Jie Li;Hong-Mei Xu;Xue-Fei Cai;De-Qiang Wang;Yuan Hu;Ni Tang;Bei-Zhong Liu
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Clinical featuresCOVID-19ImmunePaediatricsSARS-CoV-2;
59.Masks and thermometers: Paramount measures to stop the rapid spread of SARS-CoV-2 in the United States

机译：面具和温度计：最重要的措施，以阻止美国SARS-COV-2的快速传播
- 作者：Erxi Wu;Dan Qi
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- 2019-novel coronavirus (2019-nCoV)Novel coronavirus disease (COVID-19)PandemicRespiratory tractTransmission;
60.Unclear but present danger: An asymptomatic SARS-CoV-2 carrier

机译：不清楚但存在危险：一种无症状的SARS-COV-2载波
- 作者：Xuejing Yu;Dongchuan Ran;Jinhui Wang;Yuan Qin;Ruishan Liu;Xueli Shi;Yiping Wang;Chang Xie;Jia Jiang;Jianzhong Zhou
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- AsymptomaticCoronavirusCOVID-19SARS-CoV-2Superspreader;
61.Genomics functional analysis and drug screening of SARS-CoV-2

机译：SARS-COV-2基因组学功能分析及药物筛选
- 作者：Long Chen;Li Zhong
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- SARS-CoV-2Drug screeningEpitopeGenomicHomologymiRNAORF;
62.Reversible N6-methyladenosine of RNA: The regulatory mechanisms on gene expression and implications in physiology and pathology

机译：RNA的可逆N6-甲基腺苷：基因表达的调节机制和生理病理学的影响
- 作者：Xinyu Fang;Mengyang Li;Tao Yu;Gaoli Liu;Jianxun Wang
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- DiseasesEpigeneticsGene expressionm6Am6A regulatorRNA;
63.Known drugs and small molecules in the battle for COVID-19 treatment

机译：Covid-19治疗的争斗中的已知药物和小分子
- 作者：Alexios A. Panoutsopoulos
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- ChloroquineCoronavirusCOVID-19FamotidineIvermectinNicotineRemdesivirSARS-Cov2;
64.Novel SARS-CoV-2 outbreak and COVID19 disease; a systemic review on the global pandemic

机译：小说SARS-COV-2爆发和Covid 19疾病;对全球大流行的系统综述
- 作者：Abdulmohsen H. Al-Rohaimi;Faisal Al Otaibi
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Centre for disease prevention and controlCOVID19DiagnosisPandemicSARS-CoV-2TherapeuticsVaccinesWorld Health Organization;
65.CircRNA expression profiles in decidual tissue of patients with early recurrent miscarriage

机译：肝硬化组织在患者早期复发流产患者中的Circrna表达谱
- 作者：Chunli Li;Xuemei Chen;Xueqing Liu;Xiaoli Liu;Junlin He;Yubin Ding;Chao Tong;Chuan Peng;Yingxiong Wang;Rufei Gao
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Circular RNAsDecidual tissueEarly recurrent miscarriageExpression profilesMicroarray;
66.ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells

机译：通过高葡萄糖暴露在健康结肠和结肠直肠癌干细胞中引起的ROS和脂质液滴积累
- 作者：Luca Tirinato;Francesca Pagliari;Simone Di Franco;Elisa Sogne;Maria Grazia Marafioti;Jeanette Jansen;Andrea Falqui;Matilde Todaro;Patrizio Candeloro;Carlo Liberale;Joao Seco;Giorgio Stassi;Enzo Di Fabrizio
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Cholesterol metabolismColorectal cancer stem cellsFatty acid metabolismHigh glucoseLipid dropletsOncogenesOxidative stressPI3K-AKT;
67.Correlation between IL28B/TLR4 genetic variants and HCC development with/without DAAs treatment in chronic HCV patients

机译：IL28B / TLR4遗传变异与慢性HCV患者治疗的遗传变异与HCC开发的相关性
- 作者：Ghada M. Salum;Reham M. Dawood;Mai Abd el-Meguid;Noha E. Ibrahim;Ashraf O. Abdel Aziz;Mostafa K. El Awady
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- DAAsDCVHCVHCCIL28BSOFTLR4SOF SofosbuvirDCV DataclasvirDAAs Direct acting antiviral agentsHCV hepatitis C virusHCC Hepatocellular carcinomaIFNλ Type III IFNsSNP single nucleotide polymorphismSVR sustained virological responsePAMPs/DAMPs pathogen/damage associated molecular patternsTLRs toll like receptorsJAK/STAT Janus kinase/signal transducers and activators of transcriptionISGs interferon-stimulated genes;
68.Study on the hepatocellular carcinoma model with metastasis

机译：转移肝细胞癌模型研究
- 作者：Yu-Lin Lin;Yan Li
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Animal modelCell modelChemically induced HCC modelGenetically engineered mouse modelHepatocellular carcinomaMetastasisPatient derived xenograft model;
69.Epigenetic regulation of prostate cancer

机译：前列腺癌的表观遗传调节
- 作者：Ruixin Wang;Xiaoqi Liu
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- DNMTEpigeneticsEZH2HDACPhosphorylationProstate cancer;
70.Adjuvant therapies after curative treatments for hepatocellular carcinoma: Current status and prospects

机译：肝细胞癌治疗后的佐剂疗法：现状和前景
- 作者：Xiao-Dong Zhu;Kang-Shuai Li;Hui-Chuan Sun
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Adjuvant therapyAnti-PD-1 antibodyClinical trialHepatocellularcarcinomaMolecular targetedtherapyRecurrence-freesurvival;
71.High prevalence of vitamin D insufficiency in Chinese children with upper limb fractures

机译：高肢体裂缝中中国儿童维生素D不足的高患病率
- 作者：Tianjing Liu;Enbo Wang;Qiwei Li;Lianyong Li
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- AdolescentFracturePediatricUpper limbVitamin D;
72.Advances in the early diagnosis of hepatocellular carcinoma

机译：肝细胞癌早期诊断的进展
- 作者：Weiyi Wang;Chao Wei
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- BiomarkerEarly diagnosisHepatocellular carcinomaImagingLiquid biopsy;
73.Biomechanical analysis of the computer-assisted internal fixation of a?femoral neck fracture

机译：计算机辅助内部固定的生物力学分析？股骨颈骨折
- 作者：Hui Lu;Hongquan Shen;Shuqing Zhou;Weidong Ni;Dianming Jiang
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- BiomechanicsCannulated compression screwFemoral neck fractureFinite element analysisInternal fixation;
74.Identification of miRNA signature associated with BMP2 and chemosensitivity of TMZ in glioblastoma stem-like cells

机译：与BMP2相关的miRNA签名和TMZ中的胶质母细胞样细胞的化学敏感性
- 作者：Xiaoyu Guo;Ziguo Luo;Tong Xia;Lanxiang Wu;Yanshu Shi;Ying Li
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- BMP2Cancer stem cellCeRNAGliobalstomaRNA-seqTMZ;
75.The functions of N6-methyladenosine modification in lncRNAs

机译：N6-甲基腺苷改性在LNCRNA中的功能
- 作者：Rong-Zhang He;Jing Jiang;Di-Xian Luo
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- ErasersLncRNAN6-methyladenosineReadersWriters;
76.Progress in hepatectomy for hepatocellular carcinoma and peri-operation management

机译：肝细胞癌对肝细胞癌和PERI运行管理的进展
- 作者：Hao Chen;Weidong Jia
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Enhanced recovery after surgeryHepatectomyHepatocellular carcinomaPrecision medicineTreatment;
77.Adenomyosis-derived extracellular vesicles endow endometrial epithelial cells with an invasive phenotype through epithelial-mesenchymal transition

机译：腺瘤源病的细胞外囊泡赋予子宫内膜上皮细胞通过上皮 - 间充质转换具有侵入性表型
- 作者：Dayong Chen;Hai Qiao;Yiting Wang;Ling Zhou;Na Yin;Liaoqiong Fang;Zhibiao Wang
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Extracellular vesiclesEpithelial-mesenchymal transitionAdenomyosisPrimary endometrial epithelial cells;
78.Allotopic expression of mitochondrial genes: Basic strategy and progress

机译：线粒体基因的同种异体表达：基础策略与进展
- 作者：I. Made Artika
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Allotopic expressionGene therapyMitochondriaMitochondrial geneProtein targeting;
79.The fuel and engine: The roles of reprogrammed metabolism in metastasis of primary liver cancer

机译：燃料和发动机：重编程代谢在原发性肝癌转移中的作用
- 作者：Wen-Wei Zhu;Ming Lu;Xiang-Yu Wang;Xu Zhou;Chao Gao;Lun-Xiu Qin
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Amino acidCancer metastasisCholesterolFatty acidGlucosePrimary liver cancerTumormicroenvironment;
80.Whole-exome sequencing identified a novel mutation of MLH1 in an extended family with lynch syndrome

机译：全面测序鉴定了林奇综合征的大家庭中MLH1的新突变
- 作者：Hamid Ghaedi;Samira Molaei Ramsheh;Maryam Erfanian Omidvar;Afsaneh Labbaf;Elham Alehabib;Sanaz Akbari;Fatemeh Pourfatemi;Hossein Darvish
- 期刊名称：《Genes and Diseases》 | 2020年第4期
- Colorectal cancerLung cancerMismatch repairMLH1;
81.A novel FZD6 mutation revealed the cause of cleft lip and/or palate in a Chinese family

机译：一种新的FZD6突变揭示了中国家庭中唇裂和/或口感的原因
- 作者：Jieni Zhang;Huaxiang Zhao;Wenbin Huang;Fengqi Song;Wenjie Zhong;Mengqi Zhang;Yunfan Zhang;Zhibo Zhou;Jiuxiang Lin;Feng Chen
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Cleft lip and/or palateFrizzled-6Hereditary pedigreeVariantWhole-exome sequencing;
82.Ubiquitination status does not affect Vps34 degradation

机译：泛素化状态不会影响VPS34降级
- 作者：Jing Tang;Fei Sun;Xiao-Juan Deng;Yuan-Lin Ma;Kun-Yi Li;Ying Tang;Guo-Jun Chen
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Alzheimer's diseaseDegradationUbiquitinationUPSVPS34Vps34 vacuolar protein-sorting 34PI3K class III phosphatidylinositol 3-kinaseUB ubiquitinationKs lysine residuesUPS ubiquitin proteasome systemAD Alzheimer's diseaseAPP β-amyloid precursor proteinAPP/PS1 expressing Swedish APP and Presenilin1 delta exon 9 mutationsWT wild-type;
83.Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future

机译：中药作为肝癌管理的支持性护理：过去，现在和未来
- 作者：Xia Liao;Yang Bu;Qingan Jia
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Chinese herbal medicineHepatocellular carcinomaMolecular mechanismNetwork pharmacologyTraditional Chinese medicine;
84.Targeting angiogenesis for liver cancer: Past, present, and future

机译：针对肝癌的血管生成：过去，现在和未来
- 作者：Xiao-Dong Zhu;Zhao-You Tang;Hui-Chuan Sun
- 期刊名称：《Genes and Diseases》 | 2020年第3期
- Anti-angiogenictherapyCombinationaltherapyHepatocellularcarcinomaMolecular targetedtherapySystemic therapy;

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