首页>外文期刊>医学、药学、卫生>药学>Current medicinal chemistry. Central nervous system agents

Current medicinal chemistry. Central nervous system agents

中文名称：目前的药物化学。系统代理

ISSN：1568-0150
出版周期：-

发文量：40

期刊论文

热门论文

年度选择

更多>>

全选（0）

1.New trends in the development of positive allosteric modulators of ampa receptors

机译：ampa受体的正构构调节剂发展的新趋势
- 作者：E. Graindorge;P. Francotte;S. Boverie;P. de Tullio;B. Pirotte
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第2期
2.The controversial role of adenosine a_(2a) receptor antagonists as neuro-protective agents

机译：腺苷a_（2a）受体拮抗剂作为神经保护剂的争议作用
- 作者：Patrizia Popoli;David Blum;Annita Pintor;Maria Teresa Tebano;Claudio Frank;Marco Gianfriddo
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第1期
3.Primary and secondary insomnia: prevalence, causes and current therapeutics

机译：原发性和继发性失眠：患病率，病因和当前治疗方法
- 作者：Jaime M. Monti
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第2期
- sleep;
- primary insomnia;
- secondary insomnia;
- gammma-aminobutyric acid;
- alpha-subunit;
- benzodiazepine hypnotics;
- zopiclone;
- zolpidem;
- zaleplon;
4.Involvement of the endogenous opioid system in cannabinoid responses

机译：内源性阿片系统参与大麻素反应
- 作者：Olga Valverde;Patricia Robledo;Rafael Maldonado
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第3期
5.Molecular basis for the neuroprotective properties of fkbp-binding immunophilm ligands

机译：结合fkbp的免疫亲和配体的神经保护特性的分子基础
- 作者：Ken-ichi Tanaka;Norio Ogawa
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第1期
- Neuroimmunophilins;
- Non-immunosuppressive immunophilin Ligand;
- Glutathione;
- GDNF;
- BDNF;
- Apoptosis.;
6.Selegiline (iota-deprenyl) as a unique neuroprotective agent for chronic neurodegenerative disorders- a lesson from mao inhibition

机译：司来吉兰（io-deprenyl）作为一种独特的神经保护剂，可治疗慢性神经退行性疾病-从毛中抑制的教训
- 作者：Ruey-Meei Wu;Dennis L. Murphy;Chuang C. Chiueh
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
- Selegiline (deprenyl);
- MAO-B inhibitor;
- MPP~+;
- neuroprotection;
- oxidative stress;
- apoptosis;
- neurodegeneration;
- Parkinson's disease.;
7.Oxidativeitrosative brain damage in stress:possible target for neuropsychopharmacological drugs

机译：应激中的氧化性/亚硝化性脑损伤：神经心理药物的可能靶点
- 作者：Jose L.M. Madrigal;Borja Garcia-Bueno;Antonio Cardenas;Ignacio Lizasoain;Maria A Moro;Pedro Lorenzo
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
- Cyclooxygenase;
- neuroinflammation;
- neurodegeneration;
- neuroprotection nitric oxide;
- stress.;
8.Aspects of antisense oligodeoxynucleotide, ribozyme, dna enzyme and rnai design

机译：反义寡聚脱氧核苷酸，核酶，dna酶和RNAi设计的各个方面
- 作者：Barbara Grimpe
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第1期
- Neurosciences;
- Antisense;
- Ribozyme;
- DNA enzyme;
- RNAi;
- Morpholinos;
- Peptide nucleic acid;
- Locked nucleic acid.;
9.Glutamate hypothesis of schizophrenia and approach for possible therapeutic drugs

机译：精神分裂症的谷氨酸假说和可能的治疗药物的方法
- 作者：Kenji Hashimoto;Naoe Okamura;Eiji Shimizu;Masaomi lyo
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第2期
- Schizophrenia;
- Glutamate;
- NMDA receptor;
- Metabotropic glutamate receptor;
- AMPA receptor;
- Antipsychotic drugs;
- D-Serine;
- Glycine transporter inhibitor.;
10.In vivo and in vitro molecular imaging techniques to clarify the mechanism of oxidative stress related to brain aging and neuro-degenerative diseases

机译：体内和体外分子成像技术，阐明与脑衰老和神经退行性疾病有关的氧化应激机制
- 作者：Torn Sasaki
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第1期
11.Involvement of the endocannabinoid system in motor disorders

机译：内源性大麻素系统参与运动障碍
- 作者：J.J. Fernandez-Ruiz;I. Lastres-Becker;A. Cabranes;E. de Lago;J.A. Ramos
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第3期
- Cannabinoids;
- CB_1 receptors;
- endocannabinoid ligands;
- basal ganglia;
- movement;
- therapeutic potential;
- motor disorders.;
12.The anandamide degradation system as potential target for the treatment of central nervous system related disorders

机译：阿南酰胺降解系统作为治疗中枢神经系统相关疾病的潜在靶标
- 作者：Maria L. Lopez-Rodriguez;Silvia Ortega-Gutierrez
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第3期
13.Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons: possible relevance to the etiology of parkinson's disease

机译：炎性过程是黑质多巴胺能神经元变性的决定因素：可能与帕金森氏病的病因有关
- 作者：M. Tomas-Camardiel;AJ. Herrera;J.L. Venero;J.Cano;A. Machado
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
- Inflammation;
- substantia nigra;
- dopamine;
- microglia;
- LPS;
- Parkinson's disease.;
14.Magnesium as a neuroprotective agent in cerebral ischemia

机译：镁作为脑缺血的神经保护剂
- 作者：C.C. Ionita;J.F. Kirmani;A.R. Xavier;A.I. Qureshi
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
- Neuroprotection;
- excitotoxicity;
- NMDA;
- magnesium;
- stroke;
- SAH.;
15.Pompilidotoxins: novel pep tide neurotoxins blocking sodium channel inactivation from solitary wasp venom

机译：Pompilidotoxins：新型肽性神经毒素可阻断孤立性黄蜂毒液中的钠通道失活
- 作者：Katsuhiro Konno;Nobufumi Kawai
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第2期
- pompilidotoxin;
- neurotoxin;
- sodium channel inactivation;
- solitary wasp venom;
16.Development of neurochemical normalization ('agonist substitution')therapeutics for stimulant abuse: focus on the dopamine uptake inhibitor, gbr12909

机译：兴奋剂滥用的神经化学正常化（“激动剂替代”）疗法的发展：专注于多巴胺摄取抑制剂，gbr12909
- 作者：Thomas Prisinzano;Kenner C. Rice;Michael H. Baumann;Richard B. Rothman
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第1期
- GBR12909;
- dopamine;
- dopamine transporter;
- cocaine;
- and addiction.;
17.Serotonin 5-ht_7 receptor antagonists

机译：5-羟色胺5-ht_7受体拮抗剂
- 作者：M.L. Lopez-Rodriguez;B. Benhamu;M.J. Morcillo;E. Porras;J.L. Lavandera;L. Pardo
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第3期
- Serotonin;
- 5-HT_7 receptor antagonists;
- pharmacophore model;
- computational model;
- ligand-receptor interaction;
18.Cytosolic oligopeptidases: features and possible physiopathological roles in the immune and nervous systems

机译：胞质寡肽酶：在免疫和神经系统中的特征和可能的病理生理作用
- 作者：M.A.F. Hayashi;F.C.V. Portaro;A.C.M. Camargo
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
- Oligopeptidases;
- NUDEL;
- MHC class I epitopes;
- endooligopeptidase A;
- neurolysin;
- thimet oligopeptidase;
- nervous tissue;
- neuropeptides.;
19.Signal pathways mediating antidepressant and antipsychotic drugs on neuronal cell survival

机译：介导抗抑郁药和抗精神病药对神经元细胞存活的信号通路
- 作者：Anke Post;Osborne F.X. Almeida;Florian Holsboer
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第2期
20.The potential role of the endocannabinoid system in the control of multiple scleorsis

机译：内源性大麻素系统在多发性硬化症控制中的潜在作用
- 作者：David Baker;Gareth Pryce
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第3期
- Cannabis;
- cannabinoids;
- endocannabinoids;
- experimental allergic encephalomyelitis and multiple sclerosis.;
21.Dna and rna code-reading molecules as potential gene silencers in neurobiology- what are they and what are they good for?

机译：脱氧核糖核酸和脱氧核糖核酸密码阅读分子作为神经生物学中潜在的基因沉默子-它们是什么？它们有什么用？
- 作者：Marcella Faria;Carine Giovannangeli;Henning Ulrich
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
22.5-ht_3 serotonin receptor agonists: a pharmacophoric journey

机译：5-ht_3血清素受体激动剂：药效学历程
- 作者：Malgorzata Dukat
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第2期
23.Metabolism of the endocannabinoids anandamide and 2-arachidonoyl glycerol, a review, with emphasis on the pharmacology of fatty acid amide hydrolase, a possible target for the treatment of neurodegenerative diseases and pain

机译：内源性大麻素anandamide和2-arachidonoyl甘油的代谢，综述，重点是脂肪酸酰胺水解酶的药理作用，脂肪酸酰胺水解酶可能是治疗神经退行性疾病和疼痛的靶标
- 作者：Christopher J. Fowler
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第3期
- Anandamide;
- endocannabinoid;
- fatty acid amide hydrolase;
- pain;
- neurodegeneration.;
24.The neuronal histaminergic system in cognition

机译：认知中的神经元组胺能系统
- 作者：M.B. Passani;P. Blandina
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第1期
- Cholinergic system;
- Memory modulation;
- Fear conditioning;
- Passive avoidance;
- ACh release;
- Microdialysis;
- Amygdala;
- Hippocampus;
- Frontal cortex.;
25.The hydrogen peroxide and its importance in alzheimer's and parkinson's disease

机译：过氧化氢及其在阿尔茨海默氏病和帕金森氏病中的重要性
- 作者：M. Jimenez Del Rio;C. Velez-Pardo
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2004年第4期
- Alpha-Synuclein;
- Alzheimer;
- apoptosis;
- beta-amyloid;
- dopamine;
- hydrogen peroxide;
- oxygen;
- Parkinson;
- radicals;
26.Neuroactive Steroids as Targets for Development of Novel Pain Therapies

机译：神经活性类固醇作为新型疼痛疗法发展的目标。
- 作者：Slobodan M. Todorovic;Douglas F. Covey;Charles F. Zorumski;Vesna Jevtovic-Todorovic
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
- T-type channels;
- calcium;
- low voltage-activated;
- nociceptors;
- sensory neurons;
- GABAA;
- dorsal root ganglion;
27.Alzheimer's Disease and Non-Steroidal Anti-Inflammatory Drugs: Old Therapeutic Tools with Novel Mechanisms of Action?

机译：阿尔茨海默氏病和非甾体类抗炎药：具有新作用机制的旧治疗工具？
- 作者：Domenico Pratico
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
- Alzheimer's disease;
- inflammation;
- central nervous system;
- NSAIDs;
- cyclooxygenase;
- amyloid beta;
- amyloidosis;
- APP metabolism;
28.Inhibitors of Cyclin-Dependent Kinases: Potential Drugs for the Treatment of Neurodegenerative Disorders?

机译：细胞周期蛋白依赖性激酶抑制剂：治疗神经退行性疾病的潜在药物？
- 作者：Merce Pallas;Anna M. Canudas;Ester Verdaguer;Susana Garcia de Arriba;Daniel Alvira;Francesc X. Sureda
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
29.Transcriptional Dysregulation: A Therapeutic Target for Polyglutamine Diseases

机译：转录失调：聚谷氨酰胺疾病的治疗目标。
- 作者：Jonathan Cornett;Meyer Friedman;Shi-Hua Li;Xiao-Jiang Li
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
- Polyglutamine disease;
- polyQ;
- Huntington's disease;
- transcription;
- neurodegeneration;
- aggregation;
- inclusions;
30.Mechanisms of Neuropathic Pain

机译：神经性疼痛的机制
- 作者：Tony L. Yaksh;Linda S. Sorkin
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
31.CD14-Dependent Innate Immunity-Mediated Neuronal Damage in Vivo is Suppressed by NSAIDs and Ablation of a Prostaglandin E2 Receptor, EP2

机译：NSAIDs和前列腺素E2受体EP2的消除可抑制CD14依赖性先天免疫介导的体内神经元损伤。
- 作者：D. Milatovic;S. Zaja-Milatovic;K.S. Montine;M. Nivison;T.J. Montine
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
- CD14;
- innate immunity;
- neurodegeneration;
- oxidative damage;
- dendrites;
32.Current Progress in Molecular Responses to Acidosis in the Central Nervous System

机译：中枢神经系统对酸中毒的分子反应的最新进展
- 作者：Noriaki Shimokawa;Noriyuki Koibuchi
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
33.Diagnosis and Treatment of Alzheimer's Disease

机译：阿尔茨海默氏病的诊断和治疗
- 作者：Myriam Monczor
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第1期
34.Inhibition of Monoamine Neurotransmitter Transporters and Central Nervous System Stimulation Induced by Synthetic Local Anesthetics and Cocaine: A Comparative Review-Update

机译：合成局麻药和可卡因诱导单胺类神经递质转运蛋白和中枢神经系统刺激的抑制作用：综述比较更新。
- 作者：Toshihiro Dohi;Shigeo Kitayama;Katsuya Morita
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第2期
- Cocaine;
- local anesthetic;
- transporter;
- dopamine;
- reward;
- kindling;
35.Strategies to Diminish the AP Load in Alzheimer's Disease

机译：减少老年痴呆症的AP负荷的策略
- 作者：A.C.Cueilo;K.F.S.Bell
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2005年第1期
- Alzheimer's disease;
- amyloid-beta protein;
- amyloid precursor protein;
- amyloid plaques;
- secretase;
- inflammation;
- immunotherapy;
- beta-sheet breakers;
- transgenic;
36.The Secretin/Pituitary Adenylate Cyclase-Activating Polypeptide/ Vasoac-tive Intestinal Polypeptide Superfamily in the Central Nervous System

机译：分泌素/垂体腺苷酸环化酶激活多肽/血管活性肠多肽超家族在中枢神经系统中的作用
- 作者：J.Y.S. Chu;L.T.O. Lee;F.K.Y. Siu;B.K.C. Chow
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2006年第1期
37.Targeting Fatty Acid Metabolism in the Treatments of Obesity and Disorders of CNS Cellular Energy Balance

机译：靶向脂肪酸代谢治疗肥胖和中枢神经系统细胞能量平衡失调
- 作者：Leslie E. Landree;Eun-Kyoung Kim;Louise D. McCullough;Francis P. Kuhajda
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2006年第1期
- Fatty acid synthase;
- carnitine palmitoyltransferase-1;
- fatty acid metabolism;
- obesity;
- hypothalamus;
- beta-oxidation;
38.Neurosteroids in the Brain Neuron: Biosynthesis, Action and Medicinal Impact on Neurodegenerative Disease

机译：脑神经元中的类固醇：对神经退行性疾病的生物合成，作用和药物影响
- 作者：Kazuyoshi Tsutsui;Synthia H. Mellon
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2006年第1期
- Neurosteroids;
- progesterone;
- allopregnanolone;
- neuronal growth;
- synaptogenesis;
- neurodegeneration;
- Purkinje neuron;
- Niemann-Pick type C disease;
39.Elucidation of Glutamate Transporter Functions Using Selective Inhibitors

机译：使用选择性抑制剂阐明谷氨酸转运蛋白功能
- 作者：K. Shimamoto;Y. Shigeri
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2006年第1期
- Glutamate;
- neurotransmission;
- excitatory amino acid transporter;
- blocker;
- substrate;
- threo-beta-hydoxyaspartate;
- threo-beta-benzyloxy aspartate;
40.Recent Advances in Selective mu-Opioid Ligands as Evaluated in Animal Models

机译：在动物模型中评估的选择性阿片类配体的最新进展
- 作者：D.E. Dar;A. Zangen
- 期刊名称：《Current medicinal chemistry. Central nervous system agents》 | 2006年第1期
- Opioid;
- mu;
- endomorphin;
- agonist;
- antagonist;
- pain;
- addiction;

客服邮箱：kefu@zhangqiaokeyan.com

客服微信
服务号