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Current medicinal chemistry. Anti-infective agents

中文名称：目前的药物化学。

ISSN：1568-0126
出版周期：-

发文量：58

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1.Recent Progress in the Discovery of New CCR5 and CXCR4 Chemokine Receptor Antagonists as Inhibitors of HIV-1 Entry. Part 2

机译：发现新的CCR5和CXCR4趋化因子受体拮抗剂作为HIV-1进入抑制剂的最新进展。第2部分
- 作者：Wieslaw M. Kazmierski;Jennifer P. Peckham;Maosheng Duan;Terry P. Kenakin
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第2期
2.Inhibition of Farnesyltransferase as a Strategy for the Development of Novel Anti-Malarials

机译：法尼基转移酶的抑制作用作为新型抗疟疾药物开发的策略
- 作者：M. Schlitzer
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第3期
- Malaria;
- Plasmodium falciparum;
- farnesyltransferase inhibitors;
- protein prenylation;
3.CTX-M beta-Lactamases: An Update

机译：CTX-M beta-内酰胺酶：更新
- 作者：German Bou
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第3期
- CTX-M enzymes;
- structure-function;
4.The Bananins: New Anticorona-RNA-Viral Agents with Unique Structural Signature

机译：Bananins：具有独特结构特征的新型抗冠状病毒-RNA病毒剂
- 作者：Andreas J. Kesel
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2006年第2期
5.Pharmacologically Active Sulfur-Containing Compounds

机译：药理活性含硫化合物
- 作者：Tomas Rezanka;Miroslav Sobotka;Jaroslav Spizek;Karel Sigler
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2006年第2期
- Bithiazoles;
- Thiopeptides;
- Thiazole related compounds;
- Thiophenes;
- Thiolanes;
- Epipolythiodioxopiperazines;
- Six and more membered oligosulfides;
- Disulfides;
- Enediynes;
6.Advances in Chagas Disease Chemotherapy

机译：恰加斯病化学疗法的进展
- 作者：P.M.M. Guedes;J.L.R. Fietto;M. Lana;M.T. Bahia
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2006年第2期
7.Medicinal Chemistry of Ureido Derivatives as Anti-Infectives

机译：Ureido衍生物作为抗感染药的药物化学
- 作者：Sanjay Batra;Zehra Tusi;Sudharshan Madapa
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2006年第2期
8.Current Status of Target-Based Antimycobacterial Natural Products

机译：基于靶标的抗分枝杆菌天然产物的现状
- 作者：Sanjay M. Jachak;Rahul Jain
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2006年第2期
9.Discovery and Development of Antifungal Compounds

机译：抗真菌化合物的发现与开发
- 作者：M. Kidwai;R. Venkataramanan;S. Rastogi;P. Sapra
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第1期
10.Role of Deoxyribonucleoside Kinases and Deoxyribonucleotide Pool Alterations in Nucleoside Reverse Transcriptase Inhibitor Induced Mitochondrial Toxicity

机译：脱氧核糖核苷激酶和脱氧核糖核苷酸库改变在核苷逆转录酶抑制剂诱导的线粒体毒性中的作用
- 作者：K. Relucio;M. Holodniy
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第3期
11.Physico-Chemical Characterization of Drugs and Drug Forms in the Solid State

机译：固态药物和药物形式的理化特性
- 作者：A. Marini;V. Berbenni;G. Bruni;P. Cofrancesco;F. Giordano;M. Villa
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第4期
12.Anti-Infective Effects of Lactobacilli in the Gastrointestinal Tract

机译：乳酸菌在胃肠道中的抗感染作用
- 作者：H. Thorlacius;B. Jeppsson
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第4期
- Gastrointestinal tract;
- Infection;
- Lactobacilli;
- Probiotics;
13.Identification of Antifungal Agents Using Combinatorial Approach: An Overview

机译：使用组合方法鉴定抗真菌药：概述
- 作者：P. Gupta;S.K. Singh;T. Srinivasan;B. Kundu
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第2期
- Antifungal agents;
- combinatorial libraries;
- peptides;
- natural product-like structure;
- small organic molecules;
14.Current Antiviral Therapy for Chronic Hepatitis C Including Liver Transplantation and Hepatic Resection

机译：慢性丙型肝炎包括肝移植和肝切除术的当前抗病毒治疗
- 作者：Kazuhiro Hanazaki
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第2期
- hepatitis C;
- interferon;
- ribavirin;
- pegylated interferon;
- amantadine;
- liver transplantation;
- hepatic resection;
15.Selective Inhibitors of Hepatitis B Virus Replication

机译：乙型肝炎病毒复制的选择性抑制剂
- 作者：Chunxiao Ying;Erik De Clercq;Johan Neyts
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第3期
- nucleosides;
- hepatitis B virus;
- lamivudine;
- adefovir dipivoxil;
- non-nucleoside analogues;
16.Lanoconazole and Its Related Optically Active Compound NND-502:Novel Antifungal Imidazoles with a Ketene Dithioacetal Structure

机译：Lanoconazole及其相关的光学活性化合物NND-502：具有乙二乙缩醛结构的新型抗真菌咪唑
- 作者：Yoshimi Niwano;Tetsuto Ohmi;Akira Seo;Hiroki Kodama;Hiroyasu Koga;Atsusi Sakai
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第2期
- Antifungal Agent;
- Imidazole;
- Lanoconazole;
- NND-502;
17.Controlling Bacterial Infection by Inhibiting Intercellular Signalling

机译：通过抑制细胞间信号传导控制细菌感染
- 作者：M. Manefield;S. Kjelleberg;M. Givskov
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第3期
- Quorum sensing;
- Delisea;
- homoserine lactone;
- infection;
- Pseudomonas aeruginosa.;
18.Algae, A Possible Source for New Drugs in the Treatment of HIV and Other Viral Diseases

机译：藻类，可能是治疗HIV和其他病毒性疾病的新药的来源
- 作者：M. Luescher-Mattli
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第3期
- Algae;
- cyanobacteria;
- antiviral agents;
- immunomodulatory effects;
- sulfated polysaccharides;
- Cyanovirin N;
- Sulfoglycolipids;
- carrageenans.;
19.Inhibitors of Pieornavirus Replication

机译：猪瘟病毒复制的抑制剂
- 作者：Guy D. Diana
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第1期
20.Flavonoids: A Review of Its Commercial Application Potential as Anti-Infective Agents

机译：黄酮类：作为抗感染剂的商业应用潜力的审查。
- 作者：J.C. Pretorius
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第4期
- Flavonoids;
- anti-infective agents;
- application potential;
- natural products;
- review;
21.Central Nervous System Agents Used as Trypanosoma cruzi Infection Chemotherapy: Phenothiazines and Related Compounds

机译：用作克氏锥虫感染化学疗法的中枢神经系统药物：吩噻嗪和相关化合物
- 作者：P. Paglini-Oliva;H.W. Rivarola
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第4期
- Phenothiazines and related compounds;
- T.cruzi;
- chemotheraphy;
- Chagas' disease;
- chagasic cardiomyophaty.;
22.Interactions Between Antimicrobial Agents, Phagocytic Cells and Bacteria

机译：抗菌剂，吞噬细胞和细菌之间的相互作用
- 作者：W. Lee Hand
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第1期
23.Chitin Synthase As an Antifungal Target: Recent Advances

机译：几丁质合酶作为抗真菌靶标：最新进展
- 作者：J.-B. Behr
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第2期
- antifungals;
- enzyme;
- inhibition;
- chitin synthase;
- design;
- transition-state-analogues.;
24.Bioisosters of beta-Lactams as Anti-Infectives

机译：β-内酰胺的生物甾醇作为抗感染药
- 作者：Monika I. Konaklieva;Balbina J. Plotkin
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第4期
- Serine proteases;
- beta-lactamases;
- Human Leukocyte Elastase;
- serine protease inhibitors;
- beta-lactams;
- lactones;
- lactams;
- tetracyclins;
25.Discovery, Structure-Activity Relationships and Unique Properties of Non-Fluorinated Quinolones (NFQs)

机译：非氟化喹诺酮类化合物的发现，构效关系和独特性质
- 作者：Benoit Ledoussal;Ji-In K. Almstead;Jeffrey L. Gray;Eric X. Hu;Siddhartha Roychoudhury
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第1期
26.Opportunities of Finding Novel Anti-Infective Agents from Plant Cell Cultures

机译：从植物细胞培养物中发现新型抗感染剂的机会
- 作者：Ishrak Khafagi;Ahmed Dewedar;Mahamoud Amein
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第3期
- Antimicrobials;
- biotransformation;
- elicitation;
- hairy roots;
- plant cell culture.;
27.The Role of Formyl Peptide Receptors in Microbial Infection and Inflammation

机译：甲酰基肽受体在微生物感染和炎症中的作用
- 作者：Yingying Le;Ronghua Sun;Guoguang Ying;Pablo Iribarren;Ji Ming Wang
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第1期
28.Pyrimidines as Anti-Infective Agents

机译：嘧啶类抗感染药
- 作者：M. Kidwai;S. Saxena;S. Rastogi;R. Venkataramanan
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第4期
29.Anti-Infective Action of Immuno-modulating Polysaccharides ((3-Glucan and Plantago Major L. Pectin) against Intracellular (Mycobacteria sp.) and Extracellular (Streptococcus Pneumoniae sp.) Respiratory Pathogens

机译：免疫调节多糖（（3-葡聚糖和车前大果胶）对细胞内（分枝杆菌）和细胞外（肺炎链球菌）呼吸道病原菌的抗感染作用。
- 作者：Geir Hetland
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2003年第2期
- p-glucan;
- P major;
- immuno-modulation;
- macrophages;
- anti-infection effect;
- mycobacteria;
- S pneumoniae;
30.Some aspects of sialic acid modification

机译：唾液酸修饰的某些方面
- 作者：Kiyoshi Ikeda;Masayuki Sato;Yasuhiro Torisawa
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第4期
31.Antiviral marine natural products

机译：抗病毒海洋天然产物
- 作者：Kirk R. Gustafson;Naoya Oku;Dennis J. Milanowski
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第3期
32.New Therapeutic Approaches for the Treatment of Brucella Infections:Gentamicin Entrapment into Drug Delivery Systems

机译：治疗布鲁氏菌感染的新治疗方法：庆大霉素截留到药物递送系统中
- 作者：Carlos Gamazo;Maria Jose Blanco-Prieto;Maria Concepcion Lecaroz;Ana Isabel Vitas;Bruno Gander;Juan Manuel Irache
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第1期
33.Functional analysis of biosynthetic genes of aminocoumarins and production of hybrid antibiotics

机译：氨基香豆素生物合成基因的功能分析和杂交抗生素的生产
- 作者：Shu-Ming Li;Lutz Heide
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第4期
34.Antifungal compounds from marine organisms

机译：来自海洋生物的抗真菌化合物
- 作者：Tadeusz F. Molinski
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第3期
35.Cellular Immunity and DNA Vaccines for the Treatment of HIV/AIDS

机译：细胞免疫和DNA疫苗用于治疗HIV / AIDS
- 作者：F. Lori;L.M. Kelly;J. Lisziewicz
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第1期
- HIV DNA Vaccine;
- Cellular Immune Response;
- HIV Vaccine Clinical Trial;
- Cytokines;
- Vaccine Adjuvants;
- Dendritic Cell Targeted Vaccine.;
36.Preclinical Overview of WHI-07, A Novel Nucleoside Analog-based Dual-Function Microbicide

机译：新型核苷类似物双功能杀菌剂WHI-07的临床前概述
- 作者：Osmond J.DCruz;Fatih M. Uckun
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第1期
- HIV/AIDS;
- AZT;
- contraceptive;
- microbicide;
- toxicity;
- zidovudine;
37.Plant-derived leading compounds for eradication of helicobacterpylori

机译：根除幽门螺杆菌的植物来源的主要化合物
- 作者：Masami Kawase;Noboru Motohashi
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第2期
- Helicobacter pylori;
- plant-derived products;
- anti-H. pylori agents;
- anti-H. pylori activity;
- antibacterial.;
38.Ferroquine: a new weapon in the fight against malaria

机译：Ferroquine：抗击疟疾的新武器
- 作者：Christophe Biot
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第2期
- malaria;
- Plasmodium falciparum;
- chloroquine resistance;
- ferroquine;
- bioorganometallic chemistry;
39.Inhibition of microbial sialidases - what has happened beyond the influenza virus?

机译：抑制微生物唾液酸酶-除流感病毒以外发生了什么？
- 作者：Hansjorg Streicher
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第2期
- Neuraminidase;
- Sialidase;
- Inhibitors;
- N-acetylneuraminic acid;
- Sialic acid;
- Bacteria;
- Influenza virus;
- Parasites;
40.The Leading Role of Antimicrobial Agents in Modulating the Binomial Host-Microorganism

机译：抗菌剂在调节二项式宿主微生物中的主导作用
- 作者：Anna Maria Cuffini;Vivian Tullio;Narcisa Mandras;Janira Roana;Giuliana Banche;Nicola A. Carlone
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第1期
- PMNs;
- macrophages;
- antimicrobial agents;
- phagocytosis;
- killing;
- drug uptake;
- phagocyte functions.;
41.Immunomodulating Properties of Macrolides: Animal and Human Studies

机译：大环内酯类药物的免疫调节特性：动物和人类研究
- 作者：Marcus J. Schultz;Jozef Kesecioglu;Tom van der Poll
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第2期
- macrolides;
- erythromycin;
- panbronchiolitis;
- cystic fibrosis;
- chronic lung diseases;
- innate immunity;
- alveolar macrophages;
- polymorphonuclear cells;
- cytokines.;
42.Infectomics in the Discovery and Development of New Antimicrobial Agents

机译：发现和开发新的抗菌剂中的感染组学
- 作者：Sheng-He Huang;Ambrose Jong;David Warburton
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第1期
- Infectomics;
- microbial pathogens;
- chemical genomics;
- infectomes;
- host defense;
- drug discovery;
- proteomics;
- glycomics.;
43.New approaches to develop anti-staphylococcal agents

机译：开发抗葡萄球菌药物的新方法
- 作者：Lei Pei
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第4期
44.Current developments in anti-fungal agents

机译：抗真菌剂的最新发展
- 作者：A.J. Carrillo-Munoz;G. Quindos;J.L. Lopez-Ribot
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第4期
45.Inhibitors of mycothiol-s-conjugate amidase and related genes

机译：霉菌硫醇-s-共轭酰胺酶的抑制剂和相关基因
- 作者：G.M. Nicholas;C.A. Bewley
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第3期
46.Antiviral activity of natural and synthetic brassinosteroids

机译：天然和合成油菜素类固醇的抗病毒活性
- 作者：Monica B. Wachsman;Javier A. Ramirez;Laura B. Talarico;Lydia R. Galagovsky;CeliaE. Coto
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第2期
- Antiviral;
- brassinosteroids derivatives;
- Measles virus;
- Herpes simplex virus;
- Arenaviridae;
47.Molecular basis of antiretroviral drugs-associated long-term toxicity:how bad can good drugs be?

机译：抗逆转录病毒药物相关的长期毒性的分子基础：好的药物有多糟糕？
- 作者：Pere Domingo;Francesc Vidal;Joan Carles Domingo
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第2期
48.Application of radioisotopes in anti-fungal research and fungal disease studies

机译：放射性同位素在抗真菌研究和真菌疾病研究中的应用
- 作者：A.R. Jalilian;D. Sardari;S. Sardari
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第4期
- Antifungal;
- radiolabeled;
- fungal biochemistry;
- mycoses;
- fungal metabolites;
- drug discovery;
- diagnosis;
- and antifungal therapy.;
49.Discovery, SAR and Medicinal Chemistry of Herpesvirus Helicase Primase Inhibitors

机译：疱疹病毒解旋酶引发酶抑制剂的发现，SAR和药物化学
- 作者：Gerald Kleymann
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第1期
- HSV;
- Herpes;
- simplex;
- disease;
- treatment;
- drug;
- antiviral;
- agent;
- inhibitor;
- helicase;
- primase;
- BILS 179 BS;
- BILS 45 BS;
- aminothiazolyl-phenyl;
- BAY 57-1293;
- thiazolylamide.;
50.Plasticity of class a beta-lactamases, an illustration with tem and shv enzymes

机译：A类β-内酰胺酶的可塑性，以tem和shv酶为例
- 作者：Roger Labia
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第4期
51.Mining marine microorganisms as a source of new antimicrobials and antifungals

机译：开采海洋微生物作为新的抗微生物剂和抗真菌剂的来源
- 作者：V.S Bernan;M. Greenstein;G.T. Carter
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2004年第3期
- Marine;
- microorganisms;
- antibacterial;
- antifungal;
- fermentation;
- natural products.;
52.Dynamics and Structure-based Design of Drugs Targeting the Critical Serine Protease of the Hepatitis C Virus - From a Peptidic Substrate to BILN 2061

机译：动态和基于结构的药物靶向丙型肝炎病毒关键丝氨酸蛋白酶的药物设计-从肽底物到BILN 2061
- 作者：Steven R. LaPlante;Montse Llinas-Brunet
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第2期
53.Recent Progress in the Field of Antibacterial Pristinamycins

机译：抗菌素Pristinamycins领域的最新进展
- 作者：Eric Bacque;Jean-Claude Barriere;Nadine Berthaud
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第3期
- Antibacterial;
- streptogramins;
- pristinamycins;
- synergy;
- ribosome;
- structure-activity relationships;
- semi-synthesis;
54.Emergence of Multi-Drug Resistant Gram-Positive Bacteria and New Active Antibiotics

机译：多重耐药革兰氏阳性细菌和新型活性抗生素的出现
- 作者：Stefania Stefani
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第3期
- Gram-positive;
- resistance;
- multiresistant strains;
- mutations;
- genetic units;
- Oxazolidinones;
- Daptomycin;
- Ramoplanin;
- Ketolides;
- Oritavancin;
- Tigecycline;
- New fluoroquinolones;
- New cephalosporins;
55.Arylsulphones: A Promising Class of Non-Nucleoside Antiviral Agents

机译：芳砜类：非核苷类抗病毒药物的有前途的一类
- 作者：Laura Garuti;Marinella Roberti;Daniela Pizzirani;Gabriella Poggi
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第2期
- Arylsulphones;
- antiviral activity;
- HIV-1 reverse transcriptase inhibitors;
- structure-activity relationships;
- benzimidazole;
- indole;
- pyrrole;
56.Identification of Authentic Inhibitors of HIV-1 Integration

机译：鉴定HIV-1整合的真正抑制剂
- 作者：M. Witvrouw;V. Fikkert;J. Vercammen;B. Van Made
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第2期
- HIV;
- integrase;
- inhibitors;
- resistance;
- LEDGF;
57.Allosteric Inhibitors of Hepatitis C NS5B RNA-dependent RNA Polymerase

机译：丙型肝炎NS5B RNA依赖性RNA聚合酶的变构抑制剂
- 作者：Stephen M. Condon;Matthew G. LaPorte;Torsten Herbertz
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第2期
58.The Cell Wall Stress Stimulon of Staphylococcus aureus and Other Gram-Positive Bacteria

机译：金黄色葡萄球菌和其他革兰氏阳性细菌的细胞壁应激刺激
- 作者：Brian J. Wilkinson;Arunachalam Muthaiyan;Radheshyam K. Jayaswal
- 期刊名称：《Current medicinal chemistry. Anti-infective agents》 | 2005年第3期
- Cell wall stress stimulon;
- Cell wall antibiotics;
- Gram-positive bacteria;
- Staphylococcus aureus;

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