摘要:209213 A Meta-analysis of clinical outcome after mobile-bearing versus fixed-bearing for knee arthroplasty/Cao Li(Dept Orthop,1st Affil Hosp Xinjiang Med Univ,Urumqi 83054)…∥Chin J Orthop.-2009,29(2).-97~102Objective To evaluate the differences of clinical effects between mobile-bearing(MB)and fixed-bearing(FB)for knee arthroplasty using the method of Cochrane systematic review.Methods Randomized controlled trials(RCTs)on differences of clinical effects of MB or FB were identified from Ovid Medline,PubMed(1966-2008.6),Embase(1980-2008.6),Cochrane Central Register of Controlled Trials(2008)and CBM(1990-2008).All the proofs that demonstrated these issues as the RCTs were included.RevMan 4.2.10 software was used for Meta-analysis.Results Nine prospective RCTs had average 1-7.5 years follow-up,which involving 8 English and 1 German papers.The combined results of Meta-analysis indicated that there was statistical difference between two groups on post -operative maximum knee flexion(WMD=-1.63,95%CI[-2.51,-0.74],P=0.0003).Others indicated that there were no statistical differences with respect to knee society score(WMD=-0.25,95%CI[-1.09,0.59],P=0.56),patellar tilt(RD=0.01,95%CI[-0.02,0.03],P=0.64),radiological lucency around prostheses(RR=0.08,95%CI[0.61,1.29,P=0.52])and revisions of knees(RD=0.01,95%CI[-0.00,0.03],P=0.12).Conclusion Short and median follow-up indicated that although MB has statistical difference with FB on post-operative maximun flex degree of knee,but it only increase average 1.6°,and has no major clinical significance.Furthermore,there are also no major differences on knee society score,patellar track,radiological lucency around prostheses and revisions of knee,but MB has a risk of bearing dislocation.21 refs,6 figs,1 tab.