新型冠状病毒及其防治药物研究进展

摘要

The severe acute respiratory syndrome(SARS) is induced by Coronavirus(CoV), called SARS virus. SARS is called non-typical pneumonia in China. There had been“epidemic spread”of SARS in China and many countries of the world at 2003. In March of 2013, Word Health Organization(WHO) confirmed that some cases were infected by a novel coronavirus (NCoV) that had found in September of 2012. NCoV is close relative to SARS virus, and they have been paid attention to once again by scientists in the world and WHO. In this paper, the discovery, spread of NCoV, and the symptom of patient with NCoV infection are introduced. The infection mechanism of NCoV is discussed. The progress on NCoV and its preventive and therapeutic drugs is reviewed. These relative research will open up broad prospects for prevention and therapy of NCoV infection.%冠状病毒（coronavirus，COV）是引起严重急性呼吸道综合征（severe acute respiratory syndrome，SARS）的病毒，即SARS病毒（SARS virus）。SARS在我国称为非典型肺炎。2003年SARS疫情曾在中国和许多国家流行。2013年3月世界卫生组织确认几个病例是感染了曾于2012年9月发现的一种新型冠状病毒（novel coronavirus，NCoV）。新型冠状病毒与SARS病毒是近亲，属于同一病毒科，因此受到了科学家和世界卫生组织的再度关注。本文介绍了新型冠状病毒的发现和疫情蔓延、感染患者的症状，讨论了新型冠状病毒感染人体的机制，综述了新型冠状病毒及其防治药物的研究进展。这些研究为新病毒感染的预防和被感染者的治疗开拓广阔的前景。