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solvent-tolerant bacteria in biocatalysis

机译:生物催化中的耐溶剂细菌

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摘要

The toxicity of fine chemicals to the producer organism is a problem in several biotechnological production processes. In several instances, an organic phase can be used to extract the toxic product from the aqueous phase during a fermentation. With the discovery of solvent-tolerant bacteria, more solvents can now be used in such two-liquid water-solvent systems. We Are gaining new insights into the mechanisms of bacterial solvent tolerance, such as the active efflux of solvents form the Cytoplasmic membrane and solvent-impermeable outer membranes.
机译:精细化学品对生产者生物体的毒性在一些生物技术生产过程中是一个问题。在几种情况下,可以在发酵过程中使用有机相从水相中提取有毒产物。随着耐溶剂细菌的发现,现在可以在这种两液水溶剂系统中使用更多的溶剂。我们正在获得对细菌溶剂耐受性机制的新见解,例如溶剂从细胞质膜和不渗透溶剂的外膜中主动流出。

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