Cutting out the middleman: DNA biosensors based on Electrochemical oxidation

摘要

There is considerable enthusiasm over electrochemical techniques in bio- technology, including the development of electrochemical biosensors for DNA hybridisation. The development of assay techniques that have the convenience of solid-phase hybridisation and are rapid, sensitive and readily multiplexed will have a significant impact on diagnostics and genomics. Because electrochemistry requires a solid electrode, there is a natural marriage between electrode detection and surface hybridisation.