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The development of bioengineered skin

机译:生物工程皮肤的发展

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Driven by the need for donor tissue for patients suffering form extensive burns, alternatives to autologous and cadaver-derived tissue have been under development for the past 20 years. Unilayered and bilayered models representing the skin's epidermal and or dermal components have been developed using both cells and matrix materials. In addition to their use in patients with extensive burns, trials using these products on refractory and challenging patients with both acute and chronic wounds have led to he commercial availability of some of these products.
机译:在遭受广泛烧伤的患者对供体组织的需求驱使下,自体和尸体来源的组织的替代物已在过去20年中得到开发。已使用细胞和基质材料开发了代表皮肤表皮和/或真皮成分的单层和双层模型。除了将其用于严重烧伤患者之外,还在难治性和挑战性急性和慢性伤口患者上使用这些产品的试验使这些产品中的某些产品具有商业价值。

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