Predicting full-length transcripts

摘要

Accurate prediction of the complete Structures of protein-coding genes, Including 5-untranslated regions, is Crucial for full interpretation of genome Sequence. A new report describes the Statistical properties of the first exons of genes, and presents a novel statistical Method for predicting their boundaries. First exons, which are partially or Completely non-coding, have been Relatively neglected by gene-finding Algorithms. When integrated with other Genome annotation tools, this new method Will improve the technology of automated Genome interpretation.