Studies of bacterial adhesion on TiN, SiO_2-TiO_2 and hydroxyapatite thin layers deposited on titanium and Ti6A14V alloy for medical applications

摘要

The Staphylococcus epidermidis biofilm formation on titanium or titanium alloy, coated with TiN, SiO_2-TiO_2 and electrodeposited hydroxyapatite, was tested. Surfaces of titanium, Ti6Al4V alloy or TiN, modified with SiO_2-TiO_2 layer, were found to be highly resistant to bacterial adhesion. Only small amounts of bacterial cells were observed on matrices coated by thin hydroxyapatite films, deposited on both SiO_2-TiO_2 and TiN + SiO_2-TiO_2 interlayers. Biological tests showed that the biofilm formed massively on polished and ground titanium and titanium alloy surfaces, also those covered with TiN, but not on those modified with SiO_2-TiO_2 nanofilm.