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Polylactic acid coating on a biodegradable magnesium alloy: An in vitro degradation study by electrochemical impedance spectroscopy

机译:可生物降解镁合金上的聚乳酸涂层:通过电化学阻抗谱进行的体外降解研究

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摘要

Polylactic acid (PLA) was coated on a biodegradable magnesium alloy, AZ91, using spin coating technique for temporary implant applications. The degradation behaviour of the coated alloy samples was evaluated using electrochemical impedance spectroscopy (EIS) method in simulated body fluid (SBF). EIS results suggested that the PLA coating enhanced the degradation resistance of the alloy significantly. Increase in the PLA coat ing thickness was found to increase the degradation resistance, but resulted in poor adhesion. Long-term EIS experiments of the PLA coated samples suggested that their degradation resistance gradually decreased with increase in SBF exposure time. However, the degradation resistance of the PLA coated samples was signifi cantly higher than that of the bare metal even after a 48 h exposure to SBF.
机译:使用旋涂技术将聚乳酸(PLA)涂覆在可生物降解的镁合金AZ91上,用于临时植入应用。使用电化学阻抗谱(EIS)方法在模拟体液(SBF)中评估了涂层合金样品的降解行为。 EIS结果表明,PLA涂层显着提高了合金的抗降解性。发现增加PLA涂层的厚度会增加抗降解性,但导致粘合性差。 PLA涂层样品的长期EIS实验表明,随着SBF暴露时间的增加,其抗降解性逐渐降低。但是,即使暴露于SBF 48小时,PLA涂层样品的抗降解性也显着高于裸金属。

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  • 来源
    《Thin Solid Films》 |2012年第23期|p.6841-6844|共4页
  • 作者单位

    Discipline of Chemical Engineering, School of Engineering and Physical Sciences, James Cook University, Townsville, Queensland 4811, Australia;

    Discipline of Chemical Engineering, School of Engineering and Physical Sciences, James Cook University, Townsville, Queensland 4811, Australia;

    Discipline of Chemical Engineering, School of Engineering and Physical Sciences, James Cook University, Townsville, Queensland 4811, Australia;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    polylactic acid; magnesium alloy; biomaterials; biodegradation;

    机译:聚乳酸镁合金生物材料生物降解;

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