Biological effect on blood cerebrospinal fluid barrier due to radio frequency electromagnetic fields exposure of the rat brain in vivo

摘要

Concerns on health effects of radiofrequency (RF) signals have been discussed. Particularly, the effect on the central nerve system is one of main interest among the general public. So far, there are lots of studies regarding the RF effect on the Blood Brain Barrier (BBB), but no study of the RF effect on the Blood Cerebrospinal fluid Barrier (BCB). In this study we explored the effect on BCB function by radiofrequency electromagnetic fields (RF-EMF) exposure. To attain this purpose, we set about to make a real-time measuring system for BCB function using a micro-perfusion method and examined the short time exposure experiment using rats. Our data suggested the 30 min single exposure of 1.5 GHz RF-EMF at the brain average SARs of 9.5 W/kg for adult and 10.4 W/kg for juvenile, did not affect BCB function in rats under the experimental conditions.