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DOES FOCUS IMPROVE OPERATIONAL PERFORMANCE? LESSONS FROM THE MANAGEMENT OF CLINICAL TRIALS

机译:专注于提高运营绩效吗?临床试验管理的经验教训

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For over three decades, the benefits of focus have been touted under the guiding principle that dedicated attention to a small set of linked tasks improves operating performance. Numerous studies have suggested that the performance of a division, plant, or business unit is improved to the extent that it remains focused on a narrow range of activities. Others have found similar benefits associated with focus at the level of the entire firm. A question that has received less attention, however, is whether focus at the divisional level is complementary with, or a substitute for, focus at the firm level. We explore this question by considering the performance of investigative sites in biopharmaceutical clinical trials. First, we establish that firms focusing on a particular task-at either a divisional or firm level-experience higher output and productivity with respect to that task than unfocused firms. After controlling for selection, scale, and learning effects, we find that sites that focus on conducting clinical trials significantly outperform those that mix trial activity with the provision of traditional patient care. Second, we find evidence that focus at the divisional level and firm level are substitutes. That is, organizations characterized by divisional focus alone achieve statistically similar performance to sites that are characterized by both divisional and firm focus.
机译:在过去的三十多年中,人们一直将注意力集中在指导原则上,即专注于一小部分链接的任务可以改善操作性能,这是其吹捧原则。大量研究表明,部门,工厂或业务部门的绩效可以提高到一定程度,使其仍专注于狭窄的活动范围。其他人发现了与整个公司层面的关注点相关的类似好处。然而,较少受到关注的问题是,专注于部门级别是否与专注于公司级别互补或替代。我们通过考虑生物制药临床试验中研究部位的表现来探索这个问题。首先,我们确定那些专注于某个特定任务的公司(无论是部门还是公司)相对于不集中的公司,在该任务上的产出和生产率更高。在控制选择,规模和学习效果之后,我们发现专注于进行临床试验的站点明显优于那些将试验活动与传统患者护理相结合的站点。其次,我们发现有证据表明,专注于部门层面和公司层面是替代品。也就是说,仅以部门重点为特征的组织在统计上就与以部门重点和公司重点为特征的站点达到相似的绩效。

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