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Semiparametric Bayesian analysis for longitudinal mixed effects models with non-normal AR(1) errors

机译:具有非正态AR(1)误差的纵向混合效应模型的半参数贝叶斯分析

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摘要

This paper studies Bayesian inference on longitudinal mixed effects models with non-normal AR(1) errors. We model the nonparametric zero-mean noise in the autoregression residual with a Dirichlet process (DP) mixture model. Applying the empirical likelihood tool, an adjusted sampler based on the Polya urn representation of DP is proposed to incorporate information of the moment constraints of the mixing distribution. A Gibbs sampling algorithm based on the adjusted sampler is proposed to approximate the posterior distributions under DP priors. The proposed method can easily be extended to address other moment constraints owing to the wide application background of the empirical likelihood. Simulation studies are used to evaluate the performance of the proposed method. Our method is illustrated via the analysis of a longitudinal dataset from a psychiatric study.
机译:本文研究了具有非正态AR(1)误差的纵向混合效应模型的贝叶斯推断。我们使用Dirichlet过程(DP)混合模型对自回归残差中的非参数零均值噪声进行建模。运用经验似然工具,提出了一种基于DP的Polya urn表示的调整采样器,以结合混合分布的矩约束信息。提出了一种基于调整后采样器的吉布斯采样算法,以近似DP先验条件下的后验分布。由于经验似然的广泛应用背景,所提出的方法可以容易地扩展为解决其他矩约束。仿真研究用于评估所提出方法的性能。通过对精神病学研究的纵向数据集的分析说明了我们的方法。

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