Discrete-Event Models of Mixed-Phenotype Plasmodium falciparum Malaria

摘要

We extend our basic dsicrete-event model of Plasmodium falciparum malaria to encom- Pass circumstances in which multiple pheno- Typic variants of the parasite circulate within Interacting human and mosquito populations, And we compare a version in with variants Behave independently to one in which they in- Teract through shared host immune responses.