Sequencers Split Over Data Release

摘要

By the end of the session on sequencing at last week's Human Genome Organization (HUGO) meeting here, few attendees were unaware that the era of whole-genome sequencing has arrived--and with it some tough issues for the research community. After talkson the huge scale-up in sequencing capacity at two large genome centers, Andre Goffeau of the Catholic University of Louvain in Belgium announced that a multinational team has finished sequencing all 12 million bases of the baker's yeast genome, makingit the first eukaryotic genome to be completely sequenced. The achievement drew a long round of spontaneous applause from a standing-room-only audience. But the reaction was less enthusiastic when Goffeau went on to say that the final portion of the sequence (up to 20%) would not be made public until 30 April.