Coming to Crips With The Golgi

摘要

It's been exactly 100 years since the Italian biologist Camillo Golgi, working at the university in this medieval Lombardy town, peered through his microscope at spinal neurons and saw the stack of membranous structures that now bears his name. Over the decades since then, cell biologists have learned that this membranous network plays a key role in processing and transporting newly synthesized proteins. But a conference recently held here to celebrate the centennial of the Golgi apparatus showed that, despite the organelle's venerable age, research on it is still lively. Indeed, new work is forcing cell biologists to reeval-uate some of the key concepts produced by the past 10 to 15 years of work on the Golgi.