Solid Tumors In Living Color

摘要

The behavior of tumors is profoundly influenced by the microenvironment in which they grow. In addition to diffusible extracellular factors, this environment harbors a complex and dynamic population of stromal cells, including fibroblasts and a variety of immune cells. Because different types of stromal cells can have opposing effects on tumor progression and responses to therapy, it is important to understand how each cell type behaves in actively growing tumors.