Physiological Sex Predicts Hybrid Sterility Regardless of Genotype

摘要

Haldane's rule states that the heterogametic sex (ZW or XY) suffers the most negative effects of interspecific hybridization and has been observed across taxa, including fruit flies, butterflies, birds, and mammals (1, 2). The ubiquity of Haldane's rule implies that common systems isolate and maintain distinct biological species, and the mechanisms underlying Haldane's rule have been identified (2), although exceptions to this rule have been documented.