LC-MS/MS System

摘要

The TSQ Vantage is a liquid chromatography-tandem mass spec-trometry (LC-MS/MS) system that delivers up to 10 times more sensitivity than any other triple quadrupole instrument on the market, without a commensurate increase in noise. Breakthroughs in ionization efficiency and ion transmission have given the TSQ Vantage improved signal-to-noise performance, providing better reproducibility and precision in the quantitative analysis of small molecules, biomolecules, and peptides. A new S-Lens ion optics system makes use of novel electrostatic field technology to capture virtually every ion and transfer it into the HyperQuad quadrupole mass analyzer. The S-Lens is an advance over high-pressure, skimmer-based ion source designs because it eliminates mass discrimination and lowers the gas load on the expensive turbo-molecular pumps. This innovation keeps the ion optical path cleaner, for a longer period of time, while maintaining sensitivity.