机译:IDH1中胶质瘤衍生的突变主要抑制IDH1催化活性并诱导HIF-1α
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China School of Life Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China School of Life Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China School of Life Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China School of Life Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China School of Life Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, China;
Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Wuhan 430071, China;
Department of Pathology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China;
State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China;
State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China Department of Biological Chemistry, School of Medicine, Fudan University, 130 Dong-An Road, Shanghai 200032, China;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China Department of Biological Chemistry, School of Medicine, Fudan University, 130 Dong-An Road, Shanghai 200032, China Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA;
Molecular and Cell Biology Laboratory, Institute of Biomedical Sciences, Fudan University, 130 Dong-An Road, Shanghai 200032, China School of Life Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, China Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA;
机译:IDH1突变抑制星形胶质瘤中多种α-酮戊二酸依赖性双加氧酶活性
机译:IDH1突变抑制星形胶质瘤中多种α-酮戊二酸依赖性双加氧酶活性
机译:IDH1突变在星形瘤中抑制多种α-酮戊基依赖性二恶英酶活性
机译:通过非变性质谱法定量基质和抑制剂与野生型和突变体相酯脱氢酶(IDH1)的结合
机译:针对具有IDH1突变的神经胶质瘤:利用独特的代谢特征
机译:在IDH1显性禁止IDH1催化活性的神经胶质瘤衍生的突变诱导HIF-1α
机译:IDH1中的软骨肉瘤衍生突变通过诱导HIF-1α来促进肿瘤发生