Syntheses That Stay Together

摘要

An old principle of macromolecular biosynthesis in bacteria is that the speed of protein synthesis (translation) matches that of messenger RNA (mRNA) synthesis (transcription), but how this integration occurs has not been clearly defined. An obvious conjecture is that ribo-somes move along the emerging mRNA at whatever speed RNA polymerase goes so that translation and transcription remain coordinated, as it is known to do when conditions change (1).