BIOMOLECULAR INTERACTION DETECTION

摘要

The Octet RED96 system can rapidly measure protein and other biomolecule concentrations as well as determine kinetics, affinity, and specificity of protein-protein and protein-small molecule interactions. It extends the capabilities of the company's premier Octet RED platform by featuring biosensor reracking, which enables more efficient workflow, reduces amounts of capture molecule use, and lowers assay-running costs. The system enables life science researchers to perform analyses that have traditionally been conducted with SPR, HPLC, ELISA, and other single-purpose microfluidics instruments. Researchers can run a suite of assays in a multiplexed panel format using ForteBio's Protein A, Protein G, and new Protein L biosensors. The Octet platform is based on BioLayer Interferometry (BLI) technology, which uses optical biosensors to measure multiple interactions in parallel, without the use of detection agents. The Octet platform consists of 8- and 16-channel instruments that accommodate 96- and 384-well assay formats.