The Mechanics of Movement

摘要

Within cells, formin proteins promote the elongation of cytoskeletal actin filaments by associating with filament tips. This activity has the potential to harness actin-generated pushing forces to change cellular architecture. Mizuno et al. (p. 80, published online 9 December; see the Perspective by Pollard) have devised a simple method to analyze the movement of single molecules of a member of the formin family, mDial, along the growing actin filaments;