Cancer Gene Data Casts Doubt on Popular Research Method

摘要

The online catalog PubMed contains more than 25,000 biology papers about Myc, a gene linked to aggressive cancers, says David Levens, a pathologist at the National Cancer Institute in Bethesda, Maryland. But most of this work now needs to be reevaluated, according to Levens and a colleague, molecular biologist Richard Young of the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts. They argue that Myc's cancerous effects are much broader than most people have assumed, and that a flawed experimental method may have thrown off a decade's worth of Myc research.