Personalized Medicine: Temper Expectations

摘要

The 1 June Policy Forums, "The Ultimate Genetic Test" (R. Drmanac, P. 1110) And "Whole-genome sequencing: The new standard of care?" (L. R. Brunham and M. R. Hayden, p. 1112), discuss clinical breakthroughs that might be possible through whole-genome sequencing (WGS). We offer a cautionary note about the interpretation and expectations of personalized medicine and its subset, individualized drug therapy, specifically those that pertain to risk prediction in the individual patient.