HIGH-SENSITIVITY ION SOURCE

摘要

The high-sensitivity ionBooster is an ion source designed to meet the increasing demands for sensitivity enhancements in environmenta analysis, food testing, and forensics. Sensitivity gains of 5x to 100> for many compounds extend the quantitative capability of moderr accurate-mass MS systems to the sensitivity range of high-end triple-quadrupole instruments. The ion source enhances sensitivity and lowers detection limits by delivering more efficient ionization across a wide range of applications. Inside the ionBooster, an electrospray is maintained at an elevated vaporizing temperature to enable enhanced de-solvation of the analyte ions, even at high eluent flow rates in UHPLC separations with sharp chromatographic peaks. The exact response with the ionBooster depends upon the type of compound and its specific chemical characteristics and thermal properties. In combination with a maXis impact, a UHR-TOF system, accurate-mass data is obtainec across the full mass range, enabling qualitative analysis of unknowns analysis of multiple other drugs or target compounds, and retrospective screening of data for any target formula.