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Mesoamerica s Mystery Killer

机译:中美洲的神秘杀手

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A half-hour before sunrise, Emmanuel Jarquin pulls his four-wheel-drive pickup off the road near the rural town of El Paisnal and rumbles onto a sugar cane field. Jarquin, a physician, parks and steps into the sweet and smoky air, the cane having been charred the day before to burn off leaves and thorns. He walks toward the headlamps of several machete-wielding men who will start cutting at first light. "What are you bringing us?" one of the men cries in the darkness. "I'm bringing you health," Jarquin replies. Jarquin collaborates on a project studying a mysterious affliction of Central American agricultural workers known as chronic kidney disease of unknown etiology (CKDu). First reported in 2002, CKDu has no known links to diabetes or hypertension, the main causes of progressive renal damage worldwide. Much about CKDu is clouded by sketchy health statistics and the difficulty of distinguishing it from other kidney disease. But it appears to be spreading in the hot lowlands of Central America's Pacific Coast-and concerns are rising. In October, the Pan American Health Organization (PAHO) declared CKDu a "serious public health problem," with case reports streaming in from southern Mexico, Guatemala, Honduras, Nicaragua, Costa Rica, and Panama. In El Salvador alone, PAHO's latest figures say chronic kidney disease of all causes kills at least 2500 people in the country each year, and it's the main reason adults die in Salvadoran hospitals.
机译:日出前半小时,伊曼纽尔·贾昆(Emmanuel Jarquin)将他的四轮驱动皮卡从乡村小镇埃尔·佩斯纳尔(El Paisnal)附近的公路上拉了下来,轰隆隆地驶向甘蔗田。医生Jarquin停在台阶上,步入甜美而烟熏的空气中,前一天将甘蔗烧焦,烧掉了树叶和荆棘。他走向几个持弯刀的人的头灯,这些人将在第一个光线开始切割。 “你带给我们什么?”其中一个人在黑暗中哭泣。 “我为您带来健康,”贾昆回答。 Jarquin参与了一个项目,该项目研究了中美洲农业工人的一种神秘病,这种病被称为病因不明的慢性肾脏病(CKDu)。 CKDu于2002年首次报道,与糖尿病或高血压无关,而糖尿病或高血压是全世界进行性肾脏损害的主要原因。粗略的健康统计数据以及将其与其他肾脏疾病区分开的困难笼罩了很多关于CKDu的知识。但它似乎正在中美洲太平洋海岸的低地上蔓延,而且人们的担忧也在增加。十月,泛美卫生组织(PAHO)宣布CKDu为“严重的公共卫生问题”,墨西哥南部,危地马拉,洪都拉斯,尼加拉瓜,哥斯达黎加和巴拿马都有病例报道。泛美卫生组织的最新数据显示,仅在萨尔瓦多,每年因各种原因引起的慢性肾脏疾病在该国至少有2500人丧生,这是成年人在萨尔瓦多医院死亡的主要原因。

著录项

  • 来源
    《Science》 |2014年第6180期|143-147|共5页
  • 作者

    JON COHEN;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-18 02:52:23

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